Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16704599 | 0.97 | MAOA (0.39) | MAOAMAOBALDH1A1HPGDCYP1A2 | |
| SCHEMBL16704593 | 0.91 | NPC1 (0.38) | MAOAMAOBALDH1A1HPGDMEN1 | |
| SCHEMBL16704583 | 0.90 | NPC1 (0.37) | MAOAMAOBALDH1A1HPGDMEN1 | |
| SCHEMBL12686016 | 0.89 | MAPT (0.33) | MAOAMAOBALDH1A1KDM4EMEN1 | |
| SCHEMBL16704581 | 0.88 | NPC1 (0.38) | MAOAMAOBALDH1A1HPGDMEN1 | |
| SCHEMBL17536911 | 0.88 | NPC1 (0.38) | MAOAMAOBALDH1A1HPGDMEN1 | |
| SCHEMBL12470668 | 0.87 | ALDH1A1 (0.45) | MAOAMAOBALDH1A1HPGDCYP1A2 | |
| SCHEMBL16704596 | 0.85 | GABRA1 (0.38) | MAOBALDH1A1HPGDACHENPC1 | |
| SCHEMBL16704592 | 0.85 | GABRA1 (0.38) | MAOBALDH1A1HPGDACHENPC1 | |
| SCHEMBL12686018 | 0.84 | NPC1 (0.36) | ALDH1A1HPGDCYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029425-B2 | Substituted dibenzo[FG,OP]tetracenes and formulations or electronic devices containing the same | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-9029425-B2 | Substituted dibenzo[FG,OP]tetracenes and formulations or electronic devices containing the same | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |