Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25600120 | 0.84 | KCNN4 (0.35) | ALDH1A1HCAR2 | |
| SCHEMBL11326905 | 0.75 | — | — | |
| SCHEMBL8165907 | 0.73 | DGAT1 (0.39) | ALDH1A1TSHRHCAR2 | |
| SCHEMBL27973348 | 0.73 | — | — | |
| Trifluoroacetic Acid SCHEMBL17582693 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TSHRL3MBTL1THRB | |
| SCHEMBL4383211 | 0.71 | THRB (0.40) | ALDH1A1TSHRL3MBTL1THRB | |
| SCHEMBL569197 | 0.71 | TSHR (0.35) | ALDH1A1TSHRL3MBTL1THRB | |
| SCHEMBL2167176 | 0.71 | THRB (0.35) | ALDH1A1TSHRL3MBTL1THRB | |
| SCHEMBL15087844 | 0.69 | ALDH1A1 (0.36) | ALDH1A1TSHRTHRB | |
| Trifluoroacetic Acid SCHEMBL28632732 | 0.69 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1THRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673256-B1 | PROCESS FOR THE MANUFACTURE OF FLUOROMETHOXYMALONIC ACID DERIVATIVES | SOLVAY (BE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2673256-A1 | PROCESS FOR THE MANUFACTURE OF FLUOROMETHOXYMALONIC ACID DERIVATIVES | Solvay SA (BE) | 2013-12-18 | — | — | EP | disclosed |
| US-20130317251-A1 | Process for the manufacture of fluoromethoxymalonic acid derivatives | SOLVAY SA (BE) | 2013-11-28 | — | — | US | disclosed |
| US-20130317251-A1 | Process for the manufacture of fluoromethoxymalonic acid derivatives | SOLVAY SA (BE) | 2013-11-28 | — | — | US | disclosed |
| WO-2012107438-A1 | PROCESS FOR THE MANUFACTURE OF FLUOROMETHOXYMALONIC ACID DERIVATIVES | SOLVAY SA (BE) | 2012-08-16 | — | — | WO | disclosed |