Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405235 | 0.83 | ALDH1A1 (0.50) | KMT2AGAAALDH1A1KDM4ERCE1 | |
| SCHEMBL3559564 | 0.78 | KMT2A (0.55) | KMT2AALDH1A1KDM4ERCE1SMN1; SMN2 | |
| Benzene SCHEMBL3555900 | 0.78 | KMT2A (0.55) | KMT2AALDH1A1KDM4ERCE1SMN1; SMN2 | |
| Benzene SCHEMBL3558153 | 0.77 | SLC16A3 (0.63) | KMT2AALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL3558898 | 0.77 | SLC16A3 (0.63) | KMT2AALDH1A1KDM4EHPGDL3MBTL1 | |
| Benzene SCHEMBL3561698 | 0.77 | SLC16A3 (0.68) | KMT2ANR3C1RAB9A | |
| SCHEMBL3552271 | 0.77 | SLC16A3 (0.68) | KMT2ANR3C1RAB9A | |
| SCHEMBL8504969 | 0.77 | ALDH1A1 (0.45) | KMT2AALDH1A1KDM4ERCE1SMN1; SMN2 | |
| SCHEMBL7888388 | 0.76 | PTGS2 (0.54) | KMT2AGAAALDH1A1KDM4ERCE1 | |
| SCHEMBL3715386 | 0.76 | PLA2G7 (0.54) | KMT2AGAAALDH1A1KDM4ERCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018394-B2 | Method for producing aromatic compound having ring structure that includes nitrogen atom or oxygen atom | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-04-28 | — | — | US | disclosed |
| US-9018394-B2 | Method for producing aromatic compound having ring structure that includes nitrogen atom or oxygen atom | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-04-28 | — | — | US | disclosed |
| US-9018394-B2 | Method for producing aromatic compound having ring structure that includes nitrogen atom or oxygen atom | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-04-28 | — | — | US | disclosed |
| US-20130338371-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND HAVING RING STRUCTURE THAT INCLUDES NITROGEN ATOM OR OXYGEN ATOM | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2013-12-19 | — | — | US | disclosed |
| WO-2012111449-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND HAVING RING STRUCTURE THAT INCLUDES NITROGEN ATOM OR OXYGEN ATOM | 国立大学法人名古屋大学 (JP) | 2012-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338371-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND HAVING RING STRUCTURE THAT INCLUDES NITROGEN ATOM OR OXYGEN ATOM | TH, AOC3, NOX3 | KMT2A 2636/4885CA12 1903/4885CA1 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.