Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3490104 | 0.70 | ALDH1A1 (0.31) | KCNN4ALDH1A1LMNA | |
| SCHEMBL620124 | 0.70 | HSP90AA1 (0.37) | CES1TDP1LMNACYP2C19L3MBTL1 | |
| SCHEMBL28001782 | 0.69 | KCNN4 (0.32) | KCNN4KMT2A | |
| SCHEMBL7165223 | 0.69 | HSP90AA1 (0.41) | CES1MAPK1 | |
| SCHEMBL8580645 | 0.68 | HSP90AA1 (0.43) | CES1ALDH1A1 | |
| SCHEMBL896258 | 0.68 | HSP90AA1 (0.43) | CES1ALDH1A1 | |
| SCHEMBL8579302 | 0.68 | HSP90AA1 (0.43) | CES1ALDH1A1 | |
| SCHEMBL6293779 | 0.67 | KCNN4 (0.42) | CES1KCNN4ALDH1A1ALOX15LMNA | |
| SCHEMBL2821428 | 0.67 | ALDH1A1 (0.41) | CES1KCNN4ALDH1A1TDP1ALOX15 | |
| SCHEMBL28050450 | 0.67 | LMNA (0.45) | CES1KCNN4ALDH1A1ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012108863-A1 | COMPOSITIONS AND METHODS FOR CONTROLLABLY DELIVERING AN AGENT | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2012-08-16 | — | — | WO | claimed |
| US-20190125870-A1 | PHOTOCLEAVABLE DRUG CONJUGATES | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2019-05-02 | — | — | US | disclosed |
| US-10159735-B2 | Photocleavable drug conjugates | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2018-12-25 | — | — | US | disclosed |
| US-20150328314-A1 | PHOTOCLEAVABLE DRUG CONJUGATES | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2015-11-19 | — | — | US | disclosed |
| WO-2014004278-A1 | PHOTOCLEAVABLE DRUG CONJUGATES | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2014-01-03 | — | — | WO | disclosed |
| WO-2012108863-A1 | COMPOSITIONS AND METHODS FOR CONTROLLABLY DELIVERING AN AGENT | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2012-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190125870-A1 | PHOTOCLEAVABLE DRUG CONJUGATES | DHFR, CES2, STRA6 | CES1 112/4885KCNN4 4811/4885ALDH1A1 68/4885 |
| US-20150328314-A1 | PHOTOCLEAVABLE DRUG CONJUGATES | CD47, CES2, STRA6 | CES1 337/4885KCNN4 4815/4885ALDH1A1 47/4885 |
| US-10159735-B2 | Photocleavable drug conjugates | CD47, CES2, STRA6 | CES1 337/4885KCNN4 4815/4885ALDH1A1 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.