Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | KRAS | P01116 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29167245 | 0.88 | MAPT (0.51) | PLGPLAUKRASSLC6A2GLS | |
| SCHEMBL30785020 | 0.88 | MAPT (0.51) | PLGPLAUKRASSLC6A2GLS | |
| SCHEMBL2420811 | 0.84 | CYP1A2 (0.53) | PLGPLAUKRASSLC6A2GLS | |
| SCHEMBL30764997 | 0.83 | PLG (0.48) | PLGPLAUKRASSLC6A2GLS | |
| SCHEMBL5591112 | 0.83 | KRAS (0.52) | PLGPLAUKRASSLC6A2MAPT | |
| SCHEMBL3184801 | 0.83 | KRAS (0.55) | PLGPLAUKRASSLC6A2AR | |
| SCHEMBL6230447 | 0.83 | PLG (0.46) | PLGPLAUKRASSLC6A2GLS | |
| SCHEMBL13299389 | 0.82 | KRAS (0.54) | PLGPLAUKRASSLC6A2HTR7 | |
| SCHEMBL30672928 | 0.81 | PLG (0.46) | PLGPLAUKRASSLC6A2GLS | |
| SCHEMBL16371052 | 0.81 | PLG (0.46) | PLGPLAUKRASSLC6A2GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037034-A1 | E-SELECTIN ANTAGONISTS | GLYCOMIMETICS, INC. (US) | 2012-03-22 | — | — | WO | disclosed |