Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13299389 | 0.90 | KRAS (0.54) | KRASPLGPLAUCYP1A2SLC6A2 | |
| SCHEMBL3184801 | 0.85 | KRAS (0.55) | KRASPLGPLAUCYP1A2SLC6A2 | |
| SCHEMBL14876295 | 0.83 | ATM (0.55) | KRASPLGPLAUSLC6A2AR | |
| SCHEMBL2420811 | 0.83 | CYP1A2 (0.53) | KRASPLGPLAUCYP1A2SLC6A2 | |
| SCHEMBL12475322 | 0.83 | PLG (0.51) | KRASPLGPLAUCYP1A2SLC6A2 | |
| SCHEMBL30764997 | 0.82 | PLG (0.48) | KRASPLGPLAUCYP1A2SLC6A2 | |
| SCHEMBL7354759 | 0.81 | RAB9A (0.52) | KRASMAPTPPARG | |
| SCHEMBL29167245 | 0.81 | MAPT (0.51) | KRASPLGPLAUSLC6A2HTR7 | |
| SCHEMBL3355607 | 0.81 | HTR7 (0.49) | KRASPLGPLAUCYP1A2SLC6A2 | |
| SCHEMBL30785020 | 0.81 | MAPT (0.51) | KRASPLGPLAUSLC6A2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012661-A1 | HYDANTOIN DERIVED COMPOUNDS AND USE THEREOF AS MCHR-1 ANTAGONISTS | CEREP (FR) | 2007-02-01 | — | — | WO | disclosed |