SCHEMBL124760

SCHEMBL124760

CCCCCCCCCCCCCCCCCC([SiH3])(CC(C)C)CC(C)C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
THRB P10828 1/20 0.36
GGPS1 O95749 6/20 0.34
FDPS P14324 9/20 0.33
SMPD1 P17405 2/20 0.32
CES2 O00748 1/20 0.32
LPAR1 Q92633 1/20 0.32
LPAR3 Q9UBY5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10797646 0.80 TSHR (0.50) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL10416462 0.80 TSHR (0.50) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL8687202 0.80 TSHR (0.50) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL17351709 0.80 TSHR (0.50) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL16209482 0.78 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL16496835 0.75
SCHEMBL7752834 0.75 TSHR (0.41) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL28214778 0.74 TSHR (0.38) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL5964919 0.74 TSHR (0.38) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL5848545 0.74 TSHR (0.33) TSHRTHRBGGPS1FDPSSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8501788-B2 Process for recovering flunixin from pharmaceutical compositions INTERVET INC. (US) 2013-08-06 US disclosed
EP-2229149-B1 PROCESS FOR RECOVERING FLUNIXIN FROM PHARMACEUTICAL COMPOSITIONS INTERVET INT BV (NL) 2012-03-07 EP disclosed
EP-2358357-A1 PROCESS FOR RECOVERING FLORFENICOL FROM PHARMACEUTICAL COMPOSITIONS Intervet International B.V. (NL) 2011-08-24 EP disclosed
US-20100331376-A1 Process for Recovering Flunixin From Pharmaceutical Compositions INTERVET INC. 2010-12-30 US disclosed
EP-2229149-A1 PROCESS FOR RECOVERING FLUNIXIN FROM PHARMACEUTICAL COMPOSITIONS Intervet International B.V. (NL) 2010-09-22 EP disclosed
WO-2010059259-A1 PROCESS FOR RECOVERING FLORFENICOL FROM PHARMACEUTICAL COMPOSITIONS SCHERING-PLOUGH LTD. (CH) 2010-05-27 WO disclosed
US-20090170954-A1 Process for Recovering Florfenicol and Florfenicol Analogs SCHERING-PLOUGH LTD. (CH) 2009-07-02 US disclosed
WO-2009079345-A1 PROCESS FOR RECOVERING FLUNIXIN FROM PHARMACEUTICAL COMPOSITIONS SCHERING-PLOUGH LTD. (CH) 2009-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100331376-A1 Process for Recovering Flunixin From Pharmaceutical Compositions RDX, LPXN, FLNB TSHR 394/4885THRB 1625/4885GGPS1 3586/4885
US-20090170954-A1 Process for Recovering Florfenicol and Florfenicol Analogs FDPS, FAU, PFAS TSHR 2811/4885THRB 3261/4885GGPS1 127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.