⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19122443 | 1.00 | — | — | |
| SCHEMBL11945785 | 1.00 | — | — | |
| SCHEMBL17057746 | 1.00 | — | — | |
| SCHEMBL1250966 | 0.92 | — | — | |
| Isobutane SCHEMBL20607555 | 0.90 | ALDH1A1 (0.33) | — | |
| SCHEMBL14473055 | 0.89 | MET (0.37) | — | |
| SCHEMBL1249492 | 0.81 | — | — | |
| SCHEMBL1251080 | 0.78 | — | — | |
| SCHEMBL7924907 | 0.77 | OPRM1 (0.39) | — | |
| SCHEMBL18231432 | 0.76 | ACHE (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024098273-A1 | ANTI-INFLUENZA VIRUS PHOSPHATE ESTER COMPOUND AND USE THEREOF | 石家庄迪斯凯威医药科技有限公司 | 2024-05-16 | — | — | WO | disclosed |
| WO-2024098856-A1 | ANTI-INFLUENZA-VIRUS DERIVATIVES AND USE THEREOF | 石家庄迪斯凯威医药科技有限公司 | 2024-05-16 | — | — | WO | disclosed |
| US-11673864-B2 | Pyridone amides as modulators of sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-06-13 | — | — | US | disclosed |
| EP-4110782-A1 | COMPOUNDS AS CDK2/4/6 INHIBITORS | Fochon Biosciences, Ltd. (CN) | 2023-01-04 | — | — | EP | disclosed |
| CN-115551856-A | Compounds as CDK2/4/6 inhibitors | 重庆复尚源创医药技术有限公司 | 2022-12-30 | — | — | CN | disclosed |
| US-20210047271-A1 | PYRIDONE AMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMACEUTICALS (SAN DIEGO) LLC | 2021-02-18 | — | — | US | disclosed |
| US-10738009-B2 | Pyridone amides as modulators of sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-08-11 | — | — | US | disclosed |
| US-20190248745-A1 | PYRIDONE AMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED | 2019-08-15 | — | — | US | disclosed |
| US-10087143-B2 | Pyridone amides as modulators of sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-10-02 | — | — | US | disclosed |
| WO-2018081276-A1 | COMPOUNDS | TESARO, INC. (US) | 2018-05-03 | — | — | WO | disclosed |
| US-20090209580-A1 | ANTITUMOR AGENT FOR THYROID CANCER | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-08-20 | — | — | US | disclosed |
| US-20090203693-A1 | THERAPEUTIC AGENT FOR LIVER FIBROSIS | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090053236-A1 | USE OF COMBINATION OF ANTI-ANGIOGENIC SUBSTANCE AND c-kit KINASE INHIBITOR | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| CN-101253140-A | Process for the preparation of bicyclo [3.1.0] hexanols | MERCK SHARP & DOHME (GB) | 2008-08-27 | — | — | CN | disclosed |
| EP-1925676-A1 | METHOD FOR ASSAY ON THE EFFECT OF VASCULARIZATION INHIBITOR | Eisai R&D Management Co., Ltd. (JP) | 2008-05-28 | — | — | EP | disclosed |
| EP-1925941-A1 | METHOD FOR PREDICTION OF THE EFFICACY OF VASCULARIZATION INHIBITOR | Eisai R&D Management Co., Ltd. (JP) | 2008-05-28 | — | — | EP | disclosed |
| EP-1912924-A1 | A PROCESS FOR THE PREPARATION OF BICYCLO[3.1.0]HEXANOLS | Merck Sharp & Dohme Limited (GB) | 2008-04-23 | — | — | EP | disclosed |
| EP-1797877-A1 | JOINT USE OF SULFONAMIDE BASED COMPOUND WITH ANGIOGENESIS INHIBITOR | Eisai Co., Ltd. (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2007015111-A1 | A PROCESS FOR THE PREPARATION OF BICYCLO[3.1.0]HEXANOLS | MERCK SHARP & DOHME LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |
| US-20060135486-A1 | Use of sulfonamide-including compounds in combination with angiogenesis inhibitors | EISAI CO., LTD. (JP) | 2006-06-22 | — | — | US | disclosed |