Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244036 | 1.00 | NPSR1 (0.43) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL337275 | 0.80 | CCR2 (0.36) | NPSR1MAPTMEN1KMT2ACCR2 | |
| SCHEMBL4668738 | 0.78 | CHRM2 (0.45) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL11437597 | 0.76 | CCR2 (0.34) | OPRL1CCR2 | |
| SCHEMBL597190 | 0.75 | CCR2 (0.33) | CCR2 | |
| SCHEMBL27997618 | 0.73 | CYP2A6 (0.38) | LMNA | |
| SCHEMBL4753780 | 0.73 | CCR2 (0.35) | LMNACCR2 | |
| SCHEMBL5605712 | 0.71 | CCR2 (0.36) | LMNACCR2MAPK1 | |
| SCHEMBL4647450 | 0.71 | KCNA5 (0.33) | MEN1KMT2ALMNACHRNA7 | |
| SCHEMBL25428324 | 0.71 | CHRNB2 (0.34) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012113889-A1 | PROCESSES FOR THE STEREOSELECTIVE PREPARATION OF P-CHIRAL FOUR -COORDINATED PHOSPHORUS BORANE COMPOUNDS AND P-CHIRAL THREE-COORDINATED PHOSPHORUS COMPOUNDS | UNIVERSITY COLLEGE DUBLIN (IE) | 2012-08-30 | — | — | WO | disclosed |