Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12484267 | 1.00 | NPSR1 (0.43) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL337275 | 0.80 | CCR2 (0.36) | NPSR1MAPTMEN1KMT2ACCR2 | |
| SCHEMBL4668738 | 0.78 | CHRM2 (0.45) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL11437597 | 0.76 | CCR2 (0.34) | OPRL1CCR2 | |
| SCHEMBL597190 | 0.75 | CCR2 (0.33) | CCR2 | |
| SCHEMBL27997618 | 0.73 | CYP2A6 (0.38) | LMNA | |
| SCHEMBL4753780 | 0.73 | CCR2 (0.35) | LMNACCR2 | |
| SCHEMBL5605712 | 0.71 | CCR2 (0.36) | LMNACCR2MAPK1 | |
| SCHEMBL4647450 | 0.71 | KCNA5 (0.33) | MEN1KMT2ALMNACHRNA7 | |
| SCHEMBL25428324 | 0.71 | CHRNB2 (0.34) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622937-A | Polyetherimide compositions and methods for the manufacture and use thereof | SABIC INNOVATIVE PLASTICS IP BV | 2016-06-01 | — | — | CN | disclosed |
| CN-103748133-B | Polycarbonate compositions and for the preparation of with use its method | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2015-09-16 | — | — | CN | disclosed |
| CN-103764722-A | Polyetherimide compositions and methods of making and using the same | SABIC INNOVATIVE PLASTICS IP | 2014-04-30 | — | — | CN | disclosed |
| CN-103748133-A | Polycarbonate compositions and methods for the manufacture and use thereof | SABIC INNOVATIVE PLASTICS IP | 2014-04-23 | — | — | CN | disclosed |
| CN-103748129-A | Polyepoxides and epoxy resins and methods for the manufacture and use thereof | SABIC INNOVATIVE PLASTICS IP | 2014-04-23 | — | — | CN | disclosed |
| CN-103732652-A | Polysulfone compositions and methods for the manufacture and use thereof | SABIC INNOVATIVE PLASTICS IP | 2014-04-16 | — | — | CN | disclosed |
| WO-2013118118-A1 | ALPHA-HYDROGEN SUBSTITUTED NITROXYLS AND DERIVATIVES THEREOF AS CATALYSTS | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2013-08-15 | — | — | WO | disclosed |
| EP-1828089-A2 | PROCESS FOR PREPARING BISPHENOLS | General Electric Company (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006065570-A2 | PROCESS FOR PREPARING BISPHENOLS | GENERAL ELECTRIC COMPANY (US) | 2006-06-22 | — | — | WO | disclosed |
| CN-1678657-A | Bis-hydroxyphenyl menthane polyesters and polyester/polycarbonates and methods of making the same | GEN ELECTRIC (US) | 2005-10-05 | — | — | CN | disclosed |
| EP-1519976-A1 | BIS-HYDROXYPHENYL MENTHANE POLYESTERS AND POLYESTER/POLYCARBONATES AND METHODS FOR MAKING SAME | GENERAL ELECTRIC COMPANY (US) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004005367-A1 | BIS-HYDROXYPHENYL MENTHANE POLYESTERS AND POLYESTER/POLYCARBONATES AND METHODS FOR MAKING SAME | GENERAL ELECTRIC COMPANY (US) | 2004-01-15 | — | — | WO | disclosed |
| EP-0751934-B1 | SUBSTITUTED AZETIDINONE COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | SCHERING CORP (US) | 1999-08-25 | — | — | EP | disclosed |
| EP-0751934-A1 | SUBSTITUTED AZETIDINONE COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | SCHERING CORPORATION (US) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995026334-A1 | SUBSTITUTED AZETIDINONE COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | SCHERING CORPORATION (US) | 1995-10-05 | — | — | WO | disclosed |
| EP-0342904-A2 | 2-Hydroxy-3-(4-methoxyphenyl)-3-(2-aminophenylthio)propionic acid, 8'-phenylmenthyl ester, especially for diltiazem | MARION LABORATORIES, INC. (a Delaware corporation) (US) | 1989-11-23 | — | — | EP | disclosed |
| EP-0303562-A1 | Process for the preparation of E/Z mixtures of 2-(bicyclo[3.3.0]octan-3-ylidene) acetic-acid derivatives with a major proportion of E or Z isomer | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-02-15 | — | — | EP | disclosed |
| US-4187152-A | Extractive distillation for separating ketones and/or alcohols from phenol and/or cresol | ALLIED CHEMICAL CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |