Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dimethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL1157465 | 0.98 | SMN1; SMN2 (0.58) | SMN1; SMN2GAACA1CA2MMP1 | |
| Hydrochloric Acid SCHEMBL6318584 | 0.93 | GAA (0.59) | SMN1; SMN2GAACA1CA2MMP1 | |
| Hydrochloric Acid SCHEMBL2429 | 0.93 | GAA (0.59) | SMN1; SMN2GAACA1CA2MMP1 | |
| Hydrochloric Acid SCHEMBL29749149 | 0.93 | GAA (0.59) | SMN1; SMN2GAACA1CA2MMP1 | |
| Hydrochloric Acid SCHEMBL17164514 | 0.93 | GAA (0.59) | SMN1; SMN2GAACA1CA2MMP1 | |
| SCHEMBL2277355 | 0.91 | CA1 (0.58) | SMN1; SMN2GAACA1CA2MMP1 | |
| SCHEMBL344976 | 0.91 | CA1 (0.58) | SMN1; SMN2GAACA1CA2MMP1 | |
| Hydrochloric Acid SCHEMBL5379306 | 0.91 | GAA (0.56) | SMN1; SMN2GAACA1CA2MMP1 | |
| Hydrochloric Acid SCHEMBL9308912 | 0.91 | GAA (0.56) | SMN1; SMN2GAACA1CA2MMP1 | |
| Hydrochloric Acid SCHEMBL29184264 | 0.91 | GAA (0.56) | SMN1; SMN2GAACA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190530-A1 | Polycationic Viscoelastic Compositions | KNOX PAUL | 2011-08-04 | — | — | US | disclosed |
| US-7879769-B2 | Quaternary ammonium compounds with two cationic sites connected through a linker; hydraulic fluids, demulsifiers, foamers, organoclays, thickeners, biocides, and oil field fluids. | STEPAN COMPANY (US) | 2011-02-01 | — | — | US | disclosed |
| US-20080255009-A1 | Quaternary ammonium compounds with two cationic sites connected through a linker; hydraulic fluids, demulsifiers, foamers, organoclays, thickeners, biocides, and oil field fluids. | STEPAN COMPANY | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190530-A1 | Polycationic Viscoelastic Compositions | AQP1, PBRM1, PARG | SMN1; SMN2 4221/4885GAA 4072/4885CA1 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.