Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2303106 | 0.80 | ATM (0.36) | KDM4EMAPTGAAALDH1A1ELANE | |
| SCHEMBL28057497 | 0.69 | GAA (0.61) | DCTPP1MAPTGAAALDH1A1RAB9A | |
| SCHEMBL7039137 | 0.68 | GPR3 (0.39) | KDM4EMAPTGAAALDH1A1GPR3 | |
| SCHEMBL637547 | 0.68 | ALDH1A1 (0.45) | KDM4EMAPTBACE1ALDH1A1ELANE | |
| SCHEMBL558169 | 0.68 | CYP1A2 (0.39) | KDM4EMAPTGAAALDH1A1GPR3 | |
| SCHEMBL623055 | 0.68 | DCPS (0.48) | KDM4EMAPTGAAALDH1A1PKM | |
| SCHEMBL7972478 | 0.68 | PDE4A (0.48) | KDM4EMAPTALDH1A1PKMGPR3 | |
| SCHEMBL28199808 | 0.67 | GAA (0.50) | DCTPP1KDM4EMAPTBACE1GAA | |
| SCHEMBL20526115 | 0.67 | BACE1 (0.51) | KDM4EMAPTBACE1GAAALDH1A1 | |
| SCHEMBL30945013 | 0.67 | DCPS (0.57) | DCTPP1KDM4EMAPTBACE1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611502-A1 | ADENOSINE A3 RECEPTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF | Ambit Biosciences Corporation (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012030918-A1 | ADENOSINE A3 RECEPTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2012-03-08 | — | — | WO | disclosed |