Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640220 | 0.83 | ALDH1A1 (0.54) | MAPK1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL4758814 | 0.82 | HDAC1 (0.45) | MAPK1KDM4EL3MBTL1RAB9AKMT2A | |
| SCHEMBL1509187 | 0.81 | MAPK1 (0.41) | MAPK1KDM4EL3MBTL1RAB9AKMT2A | |
| SCHEMBL29508473 | 0.81 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1RAB9AKMT2A | |
| SCHEMBL69747 | 0.81 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1RAB9AKMT2A | |
| SCHEMBL30914672 | 0.80 | MAPK1 (0.40) | MAPK1KDM4EL3MBTL1RAB9ACRBN | |
| Hydrochloric Acid SCHEMBL5087052 | 0.80 | MAPK1 (0.40) | MAPK1KDM4EL3MBTL1RAB9ACRBN | |
| SCHEMBL1445644 | 0.80 | MAPK1 (0.40) | MAPK1KDM4EL3MBTL1RAB9ACRBN | |
| Acetone SCHEMBL1019109 | 0.80 | MAPK1 (0.40) | MAPK1KDM4EL3MBTL1RAB9AKMT2A | |
| SCHEMBL27076571 | 0.79 | MAPK1 (0.38) | MAPK1KDM4EL3MBTL1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11067580-B2 | Compounds and methods for conjugation of biomolecules | Life Technologies Corporation (US) | 2021-07-20 | — | — | US | disclosed |
| US-11067580-B2 | Compounds and methods for conjugation of biomolecules | Life Technologies Corporation (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200333351-A1 | Compounds and Methods for Conjugation of Biomolecules | Life Technologies Corporation | 2020-10-22 | — | — | US | disclosed |
| US-20200333351-A1 | Compounds and Methods for Conjugation of Biomolecules | Life Technologies Corporation | 2020-10-22 | — | — | US | disclosed |
| US-10648985-B2 | Compounds and methods for conjugation of biomolecules | Life Technologies Corporation (US) | 2020-05-12 | — | — | US | disclosed |
| US-10648985-B2 | Compounds and methods for conjugation of biomolecules | Life Technologies Corporation (US) | 2020-05-12 | — | — | US | disclosed |
| US-20190079095-A1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | Life Technologies Corporation | 2019-03-14 | — | — | US | disclosed |
| US-20190079095-A1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | Life Technologies Corporation | 2019-03-14 | — | — | US | disclosed |
| EP-2966061-B1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | LIFE TECHNOLOGIES CORP (US) | 2017-05-03 | — | — | EP | disclosed |
| EP-2966061-B1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | LIFE TECHNOLOGIES CORP (US) | 2017-05-03 | — | — | EP | disclosed |
| EP-2966061-A1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | Life Technologies Corporation (US) | 2016-01-13 | — | — | EP | disclosed |
| EP-2966061-A1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | Life Technologies Corporation (US) | 2016-01-13 | — | — | EP | disclosed |
| EP-2681196-B1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | LIFE TECHNOLOGIES CORP (US) | 2015-09-09 | — | — | EP | disclosed |
| EP-2681196-B1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | LIFE TECHNOLOGIES CORP (US) | 2015-09-09 | — | — | EP | disclosed |
| US-20150072396-A1 | Compounds and Methods for Conjugation of Biomolecules | Life Technologies Corporation (US) | 2015-03-12 | — | — | US | disclosed |
| EP-2681196-A1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | Life Technologies Corporation (US) | 2014-01-08 | — | — | EP | disclosed |
| WO-2012121973-A1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | Life Technologies Corporation (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012121973-A1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | Life Technologies Corporation (US) | 2012-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190079095-A1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | LIG3, LIG1, HLCS | MAPK1 2107/4885KDM4E 2864/4885L3MBTL1 1307/4885 |
| US-20200333351-A1 | Compounds and Methods for Conjugation of Biomolecules | LIG3, LIG1, HLCS | MAPK1 2107/4885KDM4E 2864/4885L3MBTL1 1307/4885 |
| US-11067580-B2 | Compounds and methods for conjugation of biomolecules | LIG3, LIG1, HLCS | MAPK1 2107/4885KDM4E 2864/4885L3MBTL1 1307/4885 |
| US-10648985-B2 | Compounds and methods for conjugation of biomolecules | LIG3, LIG1, HLCS | MAPK1 2107/4885KDM4E 2864/4885L3MBTL1 1307/4885 |
| US-20150072396-A1 | Compounds and Methods for Conjugation of Biomolecules | LIG3, LIG1, HLCS | MAPK1 2107/4885KDM4E 2864/4885L3MBTL1 1307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.