SCHEMBL1445644

SCHEMBL1445644

NNc1ccc(C(=O)ON2C(=O)CCC2=O)cn1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.40
NNMT P40261 1/20 0.39
HCAR3 P49019 7/20 0.37
MGLL Q99685 1/20 0.36
KDM4E B2RXH2 2/20 0.36
GAA P10253 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
RAB9A P51151 1/20 0.34
CRBN Q96SW2 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30914672 1.00 MAPK1 (0.40) MAPK1NNMTHCAR3MGLLKDM4E
Hydrochloric Acid SCHEMBL310253 0.99 MAPK1 (0.39) MAPK1NNMTHCAR3MGLLKDM4E
Hydrochloric Acid SCHEMBL30019344 0.99 MAPK1 (0.39) MAPK1NNMTHCAR3MGLLKDM4E
Acetone SCHEMBL1019109 0.96 MAPK1 (0.40) MAPK1NNMTHCAR3MGLLKDM4E
Acetone SCHEMBL17732269 0.95 MAPK1 (0.39) MAPK1NNMTHCAR3MGLLKDM4E
SCHEMBL28248952 0.91 NNMT (0.38) MAPK1NNMTHCAR3KDM4EGAA
SCHEMBL1509187 0.87 MAPK1 (0.41) MAPK1NNMTHCAR3MGLLKDM4E
Hydrochloric Acid SCHEMBL5087052 0.86 MAPK1 (0.40) MAPK1NNMTHCAR3MGLLKDM4E
SCHEMBL16938414 0.82 GABRP (0.49) MAPK1NNMTMGLLKDM4EGAA
SCHEMBL14603527 0.82 HCAR3 (0.38) MAPK1NNMTHCAR3MGLLKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022221706-A1 METHODS FOR ANTIBODY IDENTIFICATION AND QUANTIFICATION SEQTECH DIAGNOSTICS LLC (US) 2022-10-20 WO claimed
CN-108586621-A Targeting peptides are coupled to the method on recombination lysosomal enzyme 阿米库斯治疗学公司 2018-09-28 CN claimed
CN-104160033-B Method of coupling targeting peptides to recombinant lysosomal enzymes 阿米库斯治疗学公司 2018-06-01 CN claimed
US-20260062718-A1 CELL MEMBRANE PENETRATING CONJUGATES FOR GENE EDITING CYGENICA LTD (IE) 2026-03-05 US disclosed
US-12517133-B2 Macromolecule analysis employing nucleic acid encoding DF PEPTIDE ACQUISITION LLC 2026-01-06 US disclosed
US-12467049-B2 Methods and kits using nucleic acid encoding and/or label DF PEPTIDE ACQUISITION LLC 2025-11-11 US disclosed
US-12331310-B2 Cell membrane penetrating conjugates for gene editing CYGENICA LIMITED (IE) 2025-06-17 US disclosed
US-12320813-B2 Macromolecule analysis employing nucleic acid encoding Encodia, Inc. (US) 2025-06-03 US disclosed
US-20250164499-A1 MACROMOLECULE ANALYSIS EMPLOYING NUCLEIC ACID ENCODING DF PEPTIDE ACQUISITION LLC 2025-05-22 US disclosed
EP-3704249-B1 KITS FOR ANALYSIS USING NUCLEIC ACID ENCODING AND/OR LABEL ENCODIA INC (US) 2025-05-21 EP disclosed
US-12292446-B2 Kits for analysis using nucleic acid encoding and/or label Encodia, Inc. (US) 2025-05-06 US disclosed
EP-1351991-A2 TERNARY BIOMOLECULE/POLYMER/SURFACE-BASED IMMOBILIZATION SYSTEMS Schwartz, David A. (US) 2003-10-15 EP disclosed
US-20030186845-A1 Compositions for preventing urinary calculus NIHON MEDI-PHYSICS CO., LTD. (JP) 2003-10-02 US disclosed
EP-1323433-A1 COMPOSITIONS FOR PREVENTING URINARY CALCULUS Nihon Medi-Physics Co., Ltd. (JP) 2003-07-02 EP disclosed
US-20020146504-A1 Ternary biomolecule/polymer/surface-based immobilization systems AUDAX PRIVATE DEBT LLC, AS AGENT 2002-10-10 US disclosed
WO-2002057422-A2 TERNARY BIOMOLECULE/POLYMER/SURFACE-BASED IMMOBILIZATION SYSTEMS SCHWARTZ DAVID A (US) 2002-07-25 WO disclosed
US-6217845-B1 IMAGING; THERAPY ANORMED, INC. (CA) 2001-04-17 US disclosed
EP-0384769-B1 Protein labelling JOHNSON MATTHEY PLC (GB) 1996-04-24 EP disclosed
US-5420285-A Imaging for medicine JOHNSON MATTHEY, INC. (US) 1995-05-30 US disclosed
EP-0384769-A2 Protein labelling JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1990-08-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020146504-A1 Ternary biomolecule/polymer/surface-based immobilization systems EPCAM, DNPEP, ANPEP MAPK1 3974/4885NNMT 1358/4885HCAR3 467/4885
US-20260062718-A1 CELL MEMBRANE PENETRATING CONJUGATES FOR GENE EDITING ZFR, ZFX, ZKSCAN2 MAPK1 4517/4885NNMT 1442/4885HCAR3 4850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.