Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14984329 | 0.81 | BRD4 (0.43) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL123585 | 0.77 | L3MBTL1 (0.42) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL247107 | 0.76 | L3MBTL1 (0.41) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29951599 | 0.76 | L3MBTL1 (0.41) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29950915 | 0.76 | L3MBTL1 (0.41) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2209190 | 0.76 | L3MBTL1 (0.41) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16790819 | 0.74 | L3MBTL1 (0.39) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL124547 | 0.72 | CYP1A2 (0.44) | SMN1; SMN2NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL5678973 | 0.70 | ALDH1A1 (0.49) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL247076 | 0.69 | L3MBTL1 (0.39) | NPC1RAB9AL3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461083-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2013-06-11 | — | — | US | disclosed |
| US-8450243-B2 | Herbicidal quinoline and 1,8-naphthyridine compounds | SYNGENTA LIMITED (GB) | 2013-05-28 | — | — | US | disclosed |
| EP-2417132-B1 | HERBICIDAL QUINOLINE AND 1,8-NAPHTHYRIDINE COMPOUNDS | SYNGENTA LTD (GB) | 2013-04-17 | — | — | EP | disclosed |
| US-20120094833-A1 | HERBICIDAL QUINOLINE AND 1,8 -NAPHTHYRIDINE COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-04-19 | — | — | US | disclosed |
| EP-2265120-B1 | HERBICIDAL COUMPOUNDS | SYNGENTA LTD (GB) | 2012-03-07 | — | — | EP | disclosed |
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| EP-2265120-A1 | HERBICIDAL COUMPOUNDS | Syngenta Limited (GB) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009115788-A1 | HERBICIDAL COUMPOUNDS | SYNGENTA LIMITED (GB) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094833-A1 | HERBICIDAL QUINOLINE AND 1,8 -NAPHTHYRIDINE COMPOUNDS | NQO2, QDPR, CYP4X1 | SMN1; SMN2 4442/4885NPC1 3279/4885RAB9A 796/4885 |
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | RDX, NQO2, DDT | SMN1; SMN2 4050/4885NPC1 3417/4885RAB9A 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.