Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10146116 | 0.76 | CYP1A2 (0.37) | ALDH1A1CNR2MAPK14 | |
| SCHEMBL13618545 | 0.76 | ALDH1A1 (0.32) | ALDH1A1MAPK14 | |
| SCHEMBL10147818 | 0.71 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL10147934 | 0.71 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL1250804 | 0.70 | CNR2 (0.42) | HDAC6CNR2 | |
| SCHEMBL10146108 | 0.65 | PIK3CG (0.44) | ALDH1A1CNR2MAPK14 | |
| SCHEMBL13618560 | 0.65 | PIK3CG (0.35) | ALDH1A1CNR2 | |
| SCHEMBL10146118 | 0.64 | CNR2 (0.34) | CNR2 | |
| SCHEMBL10147579 | 0.64 | NPC1 (0.33) | MAPK14 | |
| SCHEMBL352888 | 0.63 | MAOA (0.36) | ALDH1A1CNR2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418207-A1 | Sulfone compounds which modulate the CB2 receptor | Boehringer Ingelheim International GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |