Hydrochloric Acid

Hydrochloric Acid

SCHEMBL1250828

[Cl-].c1ccc(Cc2cc[n+](Cc3ccccc3)cc2)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
SMN1; SMN2 Q16637 4/20 0.67
KDM4E B2RXH2 2/20 0.67
MEN1 O00255 1/20 0.67
MAPT P10636 1/20 0.67
KMT2A Q03164 1/20 0.67
RAB9A P51151 1/20 0.58
CHKA P35790 6/20 0.57
LMNA P02545 5/20 0.57
HTT P42858 3/20 0.57
CALM1 P0DP23 1/20 0.55
F2 P00734 1/20 0.46
PRSS1 P07477 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL5206067 0.95 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2KDM4EMEN1MAPT
Hydrochloric Acid SCHEMBL8984034 0.86 CHKA (0.59) ALDH1A1SMN1; SMN2KDM4EMEN1MAPT
Bromide SCHEMBL18321385 0.85 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2KDM4EMEN1MAPT
Hydrochloric Acid SCHEMBL5155076 0.84 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2KDM4EMEN1MAPT
Benzyl Viologen SCHEMBL1930045 0.84 ALDH1A1 (0.78) ALDH1A1SMN1; SMN2KDM4EMEN1MAPT
SCHEMBL10326023 0.84 CHKA (0.61) ALDH1A1SMN1; SMN2KDM4EMEN1MAPT
Hydrochloric Acid SCHEMBL636283 0.83 LMNA (0.63) ALDH1A1SMN1; SMN2KDM4EMEN1MAPT
SCHEMBL13283227 0.83 CHKA (0.61) ALDH1A1SMN1; SMN2KDM4EMEN1MAPT
Hydrochloric Acid SCHEMBL21061013 0.83 CHKA (0.66) ALDH1A1SMN1; SMN2KDM4EMEN1MAPT
SCHEMBL5304667 0.82 TP53 (0.64) ALDH1A1SMN1; SMN2KDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2740763-B1 FLUORORUBBER COMPOSITION NOK CORP (JP) 2016-10-12 EP disclosed
US-9441101-B2 Fluororubber composition NOK CORPORATION (JP) 2016-09-13 US disclosed
EP-2065409-B1 NOVEL FLUORINE-CONTAINING POLYMER ASAHI GLASS CO LTD (JP) 2015-04-01 EP disclosed
EP-2284144-B1 POLYFLUORO-1-ALKANE AND METHOD OF MANUFACTURE THEREFOR UNIMATEC CO LTD (JP) 2015-02-25 EP disclosed
US-20140163153-A1 FLUORORUBBER COMPOSITION NOK CORPORATION (JP) 2014-06-12 US disclosed
EP-2740763-A1 Fluororubber composition NOK CORPORATION (JP) 2014-06-11 EP disclosed
US-7956225-B2 Polyfluoro-1-alkene and method for producing the same UNIMATEC CO., LTD. (JP) 2011-06-07 US disclosed
US-7947791-B2 Fluorinated polymer ASAHI GLASS COMPANY, LIMITED (JP) 2011-05-24 US disclosed
US-20110077435-A1 POLYFLUORO-1-ALKENE AND METHOD FOR PRODUCING THE SAME UNIMATEC CO., LTD. (JP) 2011-03-31 US disclosed
EP-2284144-A1 POLYFLUORO-1-ALKANE AND METHOD OF MANUFACTURE THEREFOR Unimatec Co., Ltd. (JP) 2011-02-16 EP disclosed
US-6001932-A ACRYLIC ESTER COPOLYMER WITH VINYL ETHER, VINYL ESTER COPOLYMERS FOR RUBBER BLENDS NIPPON MEKTRON, LIMITED (JP) 1999-12-14 US disclosed
EP-0761702-B1 Novel acrylic copolymer elastomer, its blend rubber and blend rubber composition NIPPON MEKTRON KK (JP) 1999-10-27 EP disclosed
EP-0755952-B1 Acrylic copolymer elastomer, its blend rubber and blend rubber composition NIPPON MEKTRON KK (JP) 1999-10-20 EP disclosed
US-5959037-A IMPROVED COLD RESISTANCE AND AN INTERMEDIATE HEAT RESISTANCE BETWEEN THE HEAT RESISTANCE OF ACRYLIC COPOLYMER ELASTOMER AND THAT OF FLUORINE-CONTAINING ELASTOMER WHEN BLENDED WITH THE FLUORINE-CONTAINING ELASTOMER NIPPON MEKTRON, LIMITED (JP) 1999-09-28 US disclosed
US-5874506-A CONSISTS OF A TETRAMER OF VINYLIDENE FLUORIDE, TETRAFLUOROETHYLENE, HEXAFLUOROPROPYLENE AND 2H-PENTAFLUORO-PROYLENE; A POLYOL BASED CROSSLINKING AGENT AND A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT NIPPON MEKTRON, LIMITED (JP) 1999-02-23 US disclosed
US-5744562-A GOOD HEAT RESISTANCE AND AMINE RESISTANCE WITH FLUORINE-CONTAINING ELASTOMER NIPPON MEKTRON, LIMITED (JP) 1998-04-28 US disclosed
EP-0761702-A2 Novel acrylic copolymer elastomer, its blend rubber and blend rubber composition NIPPON MEKTRON, LTD. (JP) 1997-03-12 EP disclosed
EP-0755952-A2 Acrylic copolymer elastomer, its blend rubber and blend rubber composition NIPPON MEKTRON, LTD. (JP) 1997-01-29 EP disclosed
US-4734460-A STORAGE STABILITY NIPPON MEKTRON LIMITED, A CORP. OF JAPAN 1988-03-29 US disclosed
US-4032596-A QUATERNARY AMMONIUM SALTS, FREE RADICAL CATALYSTS AIR PRODUCTS AND CHEMICALS, INC. (US) 1977-06-28 US disclosed