Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | CHKA | P35790 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11598831 | 0.97 | LMNA (0.61) | LMNAALDH1A1KDM4ERAB9ACHKA | |
| SCHEMBL93665 | 0.97 | CHKA (0.59) | LMNAALDH1A1KDM4ERAB9ACHKA | |
| Hydrochloric Acid SCHEMBL31549504 | 0.95 | LMNA (0.59) | LMNAALDH1A1KDM4ERAB9ACHKA | |
| Bromide SCHEMBL28611338 | 0.95 | CHKA (0.61) | LMNAALDH1A1KDM4ERAB9ACHKA | |
| SCHEMBL28628612 | 0.95 | CHKA (0.57) | LMNAALDH1A1KDM4ERAB9ACHKA | |
| Bromide SCHEMBL365151 | 0.95 | CHKA (0.61) | LMNAALDH1A1KDM4ERAB9ACHKA | |
| Hydrochloric Acid SCHEMBL30164362 | 0.95 | CHKA (0.57) | LMNAALDH1A1KDM4ERAB9ACHKA | |
| Fluoride SCHEMBL22472142 | 0.92 | CHKA (0.55) | LMNAALDH1A1KDM4ERAB9ACHKA | |
| Hydrochloric Acid SCHEMBL28191834 | 0.92 | CHKA (0.55) | LMNAALDH1A1KDM4ERAB9ACHKA | |
| Hydrochloric Acid SCHEMBL11637202 | 0.92 | ACHE (0.61) | LMNAALDH1A1KDM4ERAB9ACHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115897065-A | Film-coated composite material and preparation method and application thereof | 吴江市新三养纺织有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115595195-A | Ceramic fiber lubricating grease and preparation method thereof | 山东鲁阳节能材料股份有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-114350343-A | Composite biological self-generated acid system for reservoir transformation | 中海油天津化工研究设计院有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-113481551-A | Electrolyte additive of electrolytic copper foil, electrolyte, electrolytic copper foil and preparation method of electrolytic copper foil | 河南科技大学 | 2021-10-08 | — | — | CN | claimed |
| US-11034817-B2 | Methods and systems for processing mixed textile feedstock, isolating constituent molecules, and regenerating cellulosic and polyester fibers | EVRNU, SPC (US) | 2021-06-15 | — | — | US | claimed |
| CN-110257041-B | Guar gum-nano cellulose fiber crosslinking thickener for fracturing fluid and preparation method thereof | 滨州学院 | 2021-05-14 | — | — | CN | claimed |
| US-20210054567-A1 | METHODS AND SYSTEMS FOR FORMING COMPOSITE FIBERS | FULL CYCLE CLIMATE PARTNERS, LP | 2021-02-25 | — | — | US | claimed |
| US-20200138710-A1 | COMPOSITIONS WITH PERMEATION ENHANCERS FOR DRUG DELIVERY | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-05-07 | — | — | US | claimed |
| CN-109761887-B | Organic dye degradation catalyst, composite catalytic material and preparation method thereof | 华南农业大学 | 2020-04-28 | — | — | CN | claimed |
| EP-3512501-A1 | COMPOSITIONS WITH PERMEATION ENHANCERS FOR DRUG DELIVERY | Children's Medical Center Corporation (US) | 2019-07-24 | — | — | EP | claimed |
| US-20160369456-A1 | METHODS AND SYSTEMS FOR PROCESSING CELLULOSE-CONTAINING MATERIALS AND ISOLATING CELLULOSE MOLECULES; METHODS FOR REGENERATING CELLULOSIC FIBERS | EVRNU, SPC | 2016-12-22 | — | — | US | claimed |
| US-20160263225-A1 | IONIC LIQUIDS FOR TRANSDERMAL DRUG DELIVERY | THE ARIZONA BOARD OF REGENTS | 2016-09-15 | — | — | US | claimed |
| EP-3062819-A2 | IONIC LIQUIDS FOR TRANSDERMAL DRUG DELIVERY | The Regents of The University of California (US) | 2016-09-07 | — | — | EP | claimed |
| WO-2015066647-A9 | IONIC LIQUIDS FOR TRANSDERMAL DRUG DELIVERY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-09-17 | — | — | WO | claimed |
| WO-2015066647-A2 | IONIC LIQUIDS FOR TRANSDERMAL DRUG DELIVERY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-05-07 | — | — | WO | claimed |
| US-20110166060-A1 | TYMPANIC MEMBRANE PERMEATING EAR DROPS AND USES THEREOF | MASSACHUSETTES INSTITUTE OF TECHNOLOGY (US) | 2011-07-07 | — | — | US | claimed |
| WO-2009142719-A2 | TYMPANIC MEMBRANE PERMEATING EAR DROPS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-11-26 | — | — | WO | claimed |
| EP-1015663-A1 | CORROSION INHIBITION THROUGH THE USE OF A QUATERNARY PYRIDINE SALT-HYDROCARBON COMBINATION | Stanchem Inc. (CA) | 2000-07-05 | — | — | EP | claimed |
| WO-1998033953-A1 | CORROSION INHIBITION THROUGH THE USE OF A QUATERNARY PYRIDINE SALT-HYDROCARBON COMBINATION | STANCHEM INC. (CA) | 1998-08-06 | — | — | WO | claimed |
| US-5093497-A | PROCESS FOR THE PREPARATION OF A SUBSTITUTED OR UNSUBSTITUTED QUINACRIDONE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200138710-A1 | COMPOSITIONS WITH PERMEATION ENHANCERS FOR DRUG DELIVERY | ABCB11, CFTR, MMP1 | ACHE 1019/4885LMNA 572/4885ALDH1A1 3578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.