Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | BCL6 | P41182 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12508799 | 0.94 | ALDH1A1 (0.56) | ALDH1A1KDM4EPSMB5TDP1NPSR1 | |
| SCHEMBL12508795 | 0.89 | TDP1 (0.68) | ALDH1A1PSMB5TDP1KMT2ACYP2C19 | |
| SCHEMBL12508801 | 0.83 | FAAH (0.59) | ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL14413602 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4EKMT2ACYP2C19NPSR1 | |
| SCHEMBL25120469 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KDM4ETDP1KMT2ACYP2C19 | |
| SCHEMBL13873127 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2ACYP2C19NPSR1 | |
| SCHEMBL12508788 | 0.78 | NAMPT (0.58) | NAMPT | |
| SCHEMBL12508798 | 0.78 | SMN1; SMN2 (0.55) | ALDH1A1KDM4EPSMB5KMT2ANAMPT | |
| SCHEMBL5267382 | 0.78 | KMT2A (0.70) | ALDH1A1KDM4EKMT2ACYP2C19NPSR1 | |
| SCHEMBL12509185 | 0.78 | FAAH (0.54) | ALDH1A1TDP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | ALDH1A1 259/4885KDM4E 1146/4885PSMB5 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.