Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.55 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.49 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.49 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.49 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.49 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12508495 | 0.94 | ALDH1A1 (0.63) | ALDH1A1PSMB5NAMPTTDP1NPSR1 | |
| SCHEMBL12508795 | 0.88 | TDP1 (0.68) | ALDH1A1PSMB5TDP1NPSR1TSHR | |
| SCHEMBL12508801 | 0.81 | FAAH (0.59) | ALDH1A1TSHRKDM4EGAA | |
| SCHEMBL12509071 | 0.79 | FAAH (0.57) | NAMPT | |
| SCHEMBL12509252 | 0.78 | FAAH (0.56) | NAMPT | |
| SCHEMBL12508798 | 0.77 | SMN1; SMN2 (0.55) | ALDH1A1PSMB5NAMPTKDM4EPSMB11 | |
| SCHEMBL12508788 | 0.77 | NAMPT (0.58) | NAMPTEPHX2 | |
| SCHEMBL12509185 | 0.76 | FAAH (0.54) | ALDH1A1FKBP1ATDP1 | |
| SCHEMBL12509069 | 0.76 | FAAH (0.56) | NAMPTMAPTNPSR1KDM4E | |
| SCHEMBL14413602 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | ALDH1A1 259/4885PSMB5 317/4885FKBP1A 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.