Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12426408 | 0.86 | LTA4H (0.41) | LTA4HPPARAPPARGBCHEACHE | |
| SCHEMBL12426453 | 0.83 | ALDH1A1 (0.39) | LTA4HPPARGBCHEACHE | |
| SCHEMBL12426479 | 0.83 | CXCR4 (0.41) | LTA4HDRD2PPARAPPARGBCHE | |
| SCHEMBL1638251 | 0.81 | DRD2 (0.40) | LTA4HDRD2HRH3BCHEACHE | |
| SCHEMBL12426462 | 0.81 | KMT2A (0.45) | KMT2A | |
| SCHEMBL12426447 | 0.80 | CXCR4 (0.41) | LTA4HDRD2PPARAPPARGBCHE | |
| SCHEMBL2204055 | 0.79 | RORC (0.47) | LTA4HHRH3 | |
| SCHEMBL12426467 | 0.78 | ALDH1A1 (0.43) | PPARGKMT2A | |
| SCHEMBL15162785 | 0.77 | LTA4H (0.42) | LTA4HDRD2BCHEACHEKMT2A | |
| SCHEMBL15162786 | 0.77 | LTA4H (0.42) | LTA4HDRD2BCHEACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977512-B2 | Amine derivative, and production method and use thereof | KUREHA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |