Sugi Predict

Sugi Predict / Compounds / SCHEMBL1252183

SCHEMBL1252183

SCHEMBL1252183

CN(C(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21)c1ccc(C(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 1/20 0.49
▸ KMT2A Q03164 3/20 0.49
▸ EPHX2 P34913 1/20 0.42
▸ CASP3 P42574 2/20 0.41
▸ FABP7 O15540 1/20 0.39
▸ FABP5 Q01469 1/20 0.39
▸ TLR2 O60603 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28803723 0.92 OPRD1 (0.56) OPRD1KMT2AEPHX2CASP3FABP7
SCHEMBL18170903 0.83 FABP5 (0.44) KMT2AEPHX2CASP3FABP7FABP5
SCHEMBL24406209 0.80 KMT2A (0.56) OPRD1KMT2AEPHX2CASP3FABP7
SCHEMBL30367121 0.80 KMT2A (0.56) OPRD1KMT2AEPHX2CASP3FABP7
SCHEMBL18859026 0.79 KMT2A (0.52) OPRD1KMT2AEPHX2CASP3FABP7
SCHEMBL28669272 0.79 KMT2A (0.49) OPRD1KMT2AEPHX2CASP3FABP7
SCHEMBL29678978 0.78 KMT2A (0.56) OPRD1KMT2AEPHX2CASP3FABP7
SCHEMBL118108 0.78 KMT2A (0.56) OPRD1KMT2AEPHX2CASP3FABP7
SCHEMBL29402075 0.78 KMT2A (0.56) OPRD1KMT2AEPHX2CASP3FABP7
SCHEMBL1252186 0.78 KMT2A (0.51) OPRD1KMT2AEPHX2CASP3FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130136691-A1 GASTRIN RELEASING PEPTIDE COMPOUNDS BRACCO IMAGING S.P.A. (IT) 2013-05-30 — — US disclosed
US-20130136691-A1 GASTRIN RELEASING PEPTIDE COMPOUNDS BRACCO IMAGING S.P.A. (IT) 2013-05-30 — — US disclosed
US-8444954-B2 Gastrin releasing peptide compounds BRACCO IMAGING S.P.A. (IT) 2013-05-21 — — US disclosed
US-8420053-B2 Gastrin releasing peptide compounds BRACCO IMAGING S.P.A. (IT) 2013-04-16 — — US disclosed
US-8420050-B2 Gastrin releasing peptide compounds BRACCO IMAGING S.P.A. (IT) 2013-04-16 — — US disclosed
US-8420050-B2 Gastrin releasing peptide compounds BRACCO IMAGING S.P.A. (IT) 2013-04-16 — — US disclosed
EP-2500040-A1 Improved Gastrin Releasing Peptide Receptor-Binding Compounds Bracco Imaging S.p.A (IT) 2012-09-19 — — EP disclosed
EP-2500040-A1 Improved Gastrin Releasing Peptide Receptor-Binding Compounds Bracco Imaging S.p.A (IT) 2012-09-19 — — EP disclosed
US-20120009122-A1 GASTRIN RELEASING PEPTIDE COMPOUNDS BRACCO IMAGING S.P.A. (IT) 2012-01-12 — — US disclosed
US-20110250133-A1 GASTRIN RELEASING PEPTIDE COMPOUNDS BRACCO IMAGING S.P.A. (IT) 2011-10-13 — — US disclosed
WO-2007095443-A2 GASTRIN RELEASING PEPTIDE COMPOUNDS BRACCO IMAGING S.P.A. (IT) 2007-08-23 — — WO disclosed
WO-2007002500-A1 GASTRIN RELEASING PEPTIDE COMPOUNDS BRACCO IMAGING S.P.A. (IT) 2007-01-04 — — WO disclosed
US-20060239914-A1 Gastrin releasing peptide compounds BRACCO IMAGING S.P.A. (IT) 2006-10-26 — — US disclosed
US-20060239923-A1 Gastrin releasing peptide compounds BRACCO IMAGING S.P.A. (IT) 2006-10-26 — — US disclosed
EP-1706154-A1 IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS Bracco Imaging, S.P.A. (IT) 2006-10-04 — — EP disclosed
US-20060018830-A1 Gastrin releasing peptide compounds BRACCO IMAGING S.P.A. (IT) 2006-01-26 — — US disclosed
EP-1585549-A2 IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS Bracco Imaging S.p.A. (IT) 2005-10-19 — — EP disclosed
WO-2005067983-A1 IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS BRACCO IMAGING S.P.A. (IT) 2005-07-28 — — WO disclosed
US-20040253225-A1 bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy BRACCO IMAGING S.P.A. (IT) 2004-12-16 — — US disclosed
WO-2004065407-A2 IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS BRACCO IMAGING S.P.A. (IT) 2004-08-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060239914-A1 Gastrin releasing peptide compounds GRPR, GIPR, CCKBR OPRD1 780/4885KMT2A 2523/4885EPHX2 3656/4885
US-20130136691-A1 GASTRIN RELEASING PEPTIDE COMPOUNDS GRPR, GIPR, GHRHR OPRD1 1148/4885KMT2A 4582/4885EPHX2 4140/4885
US-20040253225-A1 bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy GRPR, MLNR, NPBWR1 OPRD1 657/4885KMT2A 4045/4885EPHX2 3747/4885
US-20060239923-A1 Gastrin releasing peptide compounds GRPR, GIPR, CCKBR OPRD1 534/4885KMT2A 4189/4885EPHX2 2802/4885
US-20060018830-A1 Gastrin releasing peptide compounds GRPR, GIPR, CCKBR OPRD1 780/4885KMT2A 2523/4885EPHX2 3656/4885
US-20120009122-A1 GASTRIN RELEASING PEPTIDE COMPOUNDS GRPR, GIPR, CCKBR OPRD1 780/4885KMT2A 2523/4885EPHX2 3656/4885
US-20110250133-A1 GASTRIN RELEASING PEPTIDE COMPOUNDS GRPR, GIPR, GHRHR OPRD1 1148/4885KMT2A 4582/4885EPHX2 4140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.