SCHEMBL12522293

SCHEMBL12522293

Bc1ccc(/C=C/c2ccc3c(c2)C2(c4cc(/C=C/c5ccc(Br)cc5)ccc4-3)c3cc(OCC(C)CC)c(OCC(C)CC)cc3-c3cc(OCC(C)CC)c(OCC(C)CC)cc32)cc1

nearest known ligand 0.31

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31
TUBB3 Q13509 1/20 0.31
TUBB2A Q13885 1/20 0.31
TUBB8 Q3ZCM7 1/20 0.31
TUBA3E Q6PEY2 1/20 0.31
TUBA1A Q71U36 1/20 0.31
TUBA1C Q9BQE3 1/20 0.31
TUBB6 Q9BUF5 1/20 0.31
TUBB2B Q9BVA1 1/20 0.31
TUBB1 Q9H4B7 1/20 0.31
CHRNA7 P36544 1/20 0.30
IGF1R P08069 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL679086 0.95 TUBB4A (0.34) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL14441624 0.89 KMT2A (0.33) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL13161611 0.88 AKR1C3 (0.31) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL13376510 0.85 TLR8 (0.32)
SCHEMBL14306944 0.85 NFE2L2 (0.34) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL14314033 0.82
SCHEMBL13198868 0.82 TLR8 (0.36) IGF1R
SCHEMBL680229 0.82 TLR8 (0.36) IGF1R
SCHEMBL18062069 0.82 PDE4B (0.35) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL17849115 0.82 PDK2 (0.36) TUBB1CHRNA7IGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1932866-B1 Blends comprising conjugated carbazole polymers, synthesis and usage thereof MERCK PATENT GMBH (DE) 2011-07-13 EP disclosed
EP-1741148-B1 ELECTROLUMINESCENT POLYMERS COMPRISING PLANAR ARYLAMINE UNITS THE PREPARATION AND USE THEREOF MERCK PATENT GMBH (DE) 2009-06-03 EP disclosed
EP-1741149-B1 ELECTROLUMINESCENT POLYMERS AND USE THEROF MERCK PATENT GMBH (DE) 2008-12-24 EP disclosed
EP-1932866-A1 Blends comprising conjugated carbazole polymers, synthesis and usage thereof MERCK PATENT GmbH (DE) 2008-06-18 EP disclosed
EP-1656407-B1 CONJUGATED COPOLYMERS, REPRESENTATION AND USE THEREOF MERCK PATENT GMBH (DE) 2008-03-12 EP disclosed