Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14306944 | 0.97 | NFE2L2 (0.34) | PDK2MTORCYP3A4NPC1TP53 | |
| SCHEMBL18062069 | 0.94 | PDE4B (0.35) | IGF1RTLR8NFE2L2AKR1C3TUBB1 | |
| SCHEMBL19007776 | 0.90 | IGF1R (0.31) | PDK2IGF1RSMN1; SMN2NFE2L2 | |
| SCHEMBL679086 | 0.87 | TUBB4A (0.34) | PDK2IGF1RCHRNA7TLR8TUBB1 | |
| SCHEMBL13956686 | 0.84 | — | — | |
| SCHEMBL4546505 | 0.84 | TLR8 (0.36) | PDK2IGF1RKDM4ETDP1TLR8 | |
| SCHEMBL12595641 | 0.84 | TLR8 (0.36) | PDK2IGF1RKDM4ETDP1TLR8 | |
| SCHEMBL17153143 | 0.83 | TLR8 (0.38) | PDK2NPC1IGF1RTLR8 | |
| SCHEMBL13205036 | 0.83 | TLR8 (0.38) | PDK2NPC1IGF1RTLR8 | |
| SCHEMBL12522293 | 0.82 | TUBB4A (0.31) | IGF1RCHRNA7TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9373807-B2 | Radiative fibers | MERCK PATENT GMBH (DE) | 2016-06-21 | — | — | US | disclosed |