Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2685237 | 0.82 | CES2 (0.61) | FBP1ALDH1A1CES1BRAFTDP1 | |
| SCHEMBL2685238 | 0.82 | CES2 (0.61) | FBP1ALDH1A1CES1BRAFTDP1 | |
| SCHEMBL5434503 | 0.82 | ESR1 (0.66) | FBP1TSHRALDH1A1CES1CA1 | |
| SCHEMBL5685314 | 0.82 | ESR1 (0.66) | FBP1TSHRALDH1A1CES1CA1 | |
| SCHEMBL19439752 | 0.82 | ESR1 (0.66) | FBP1TSHRALDH1A1CES1CA1 | |
| SCHEMBL12973308 | 0.82 | PTGS2 (0.59) | FBP1TSHRALDH1A1CYP2C19LOXL2 | |
| Paranitrobenzyl Alcohol SCHEMBL114620 | 0.81 | TSHR (0.69) | TSHRALDH1A1CYP2C19CES1CA1 | |
| SCHEMBL27942881 | 0.80 | BCHE (0.59) | FBP1ALDH1A1CES1BRAFTDP1 | |
| SCHEMBL413193 | 0.78 | SRD5A2 (0.65) | TSHRALDH1A1CES1CA1CA2 | |
| SCHEMBL5681533 | 0.77 | MAPT (0.70) | ALDH1A1KDM4EMAPTSMN1; SMN2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409859-B2 | Substituted diphenyl derivatives | CREATIVE THERAPEUTICS GMBH (DE) | 2016-08-09 | — | — | US | disclosed |
| WO-2012122969-A1 | SUBSTITUTED DIPHENYL DERIVATIVES | CREATIVE THERAPEUTICS GMBH (DE) | 2012-09-20 | — | — | WO | disclosed |
| US-20070099876-A1 | Target directed chemotherapy of tumours of the sexual organs | TRIN GMBH (CH) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099876-A1 | Target directed chemotherapy of tumours of the sexual organs | GPER1, SHBG, GNRHR | FBP1 3493/4885TSHR 1181/4885ALDH1A1 769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.