Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.66 |
| ▸ | FBP1 | P09467 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685314 | 1.00 | ESR1 (0.66) | ESR1ESR2FBP1PTGS2PTGS1 | |
| SCHEMBL19439752 | 1.00 | ESR1 (0.66) | ESR1ESR2FBP1PTGS2PTGS1 | |
| SCHEMBL2685237 | 0.86 | CES2 (0.61) | ESR1FBP1PTGS2CES1TDP1 | |
| SCHEMBL2685238 | 0.86 | CES2 (0.61) | ESR1FBP1PTGS2CES1TDP1 | |
| SCHEMBL27942881 | 0.84 | BCHE (0.59) | FBP1PTGS2CES1TDP1ALDH1A1 | |
| SCHEMBL9139326 | 0.83 | FBP1 (0.58) | FBP1PTGS2PTGS1CES1CA1 | |
| SCHEMBL9135315 | 0.83 | ESR1 (0.68) | ESR1ESR2FBP1PTGS2PTGS1 | |
| SCHEMBL9139328 | 0.83 | FBP1 (0.58) | FBP1PTGS2PTGS1CES1CA1 | |
| SCHEMBL9135312 | 0.83 | ESR1 (0.68) | ESR1ESR2FBP1PTGS2PTGS1 | |
| SCHEMBL12523909 | 0.82 | FBP1 (0.49) | ESR1ESR2FBP1CES1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099876-A1 | Target directed chemotherapy of tumours of the sexual organs | TRIN GMBH (CH) | 2007-05-03 | — | — | US | disclosed |
| US-20070099876-A1 | Target directed chemotherapy of tumours of the sexual organs | TRIN GMBH (CH) | 2007-05-03 | — | — | US | disclosed |
| US-20070099876-A1 | Target directed chemotherapy of tumours of the sexual organs | TRIN GMBH (CH) | 2007-05-03 | — | — | US | disclosed |
| EP-1636249-A1 | TARGET-ORIENTED CHEMOTHERAPY FOR TREATING TUMORS OF THE SEXUAL ORGANS | TRIN GmbH (CH) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004106358-A1 | TARGET-ORIENTED CHEMOTHERAPY FOR TREATING TUMORS OF THE SEXUAL ORGANS | TRIN GMBH (CH) | 2004-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099876-A1 | Target directed chemotherapy of tumours of the sexual organs | GPER1, SHBG, GNRHR | ESR1 4/4885ESR2 5/4885FBP1 3493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.