SCHEMBL12528531

SCHEMBL12528531

Cc1cc(Br)cn1-c1ncccc1Cl

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 4/20 0.40
HSD11B1 P28845 3/20 0.37
MALT1 Q9UDY8 1/20 0.35
CYP17A1 P05093 1/20 0.34
CYP1A2 P05177 1/20 0.34
PHGDH O43175 1/20 0.34
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RPS6KA5 O75582 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12528652 0.84 TRPV1 (0.42) TRPV1HSD11B1MALT1CYP17A1CYP1A2
SCHEMBL12528798 0.84 MYC (0.34) CYP1A2KDM4ESMN1; SMN2
SCHEMBL12528693 0.81 TRPV1 (0.40) TRPV1HSD11B1MALT1CYP17A1CYP1A2
SCHEMBL12528756 0.78 EPHX2 (0.43) HSD11B1PHGDH
SCHEMBL12528740 0.78 MYC (0.31)
SCHEMBL950752 0.78 ALDH1A1 (0.36) TRPV1HSD11B1MALT1ALDH1A1SMN1; SMN2
SCHEMBL951639 0.77 MALT1 (0.38) MALT1SMN1; SMN2
SCHEMBL339159 0.76 POLB (0.41) MALT1CYP1A2ALDH1A1
SCHEMBL12528529 0.73 TRPV1 (0.41) TRPV1HSD11B1MALT1CYP17A1CYP1A2
SCHEMBL12528846 0.72 TRPV1 (0.38) TRPV1HSD11B1MALT1CYP17A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968573-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-28 US disclosed
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME IKEGAMI HIROSHI 2011-03-24 US disclosed
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME ACHE, H1-2, H1-0 TRPV1 1056/4885HSD11B1 1797/4885MALT1 4856/4885
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT TRPV1 687/4885HSD11B1 651/4885MALT1 4865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.