SCHEMBL12528529

SCHEMBL12528529

Cc1cccn1-c1ncccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 3/20 0.41
HSD11B1 P28845 3/20 0.40
RPS6KA5 O75582 5/20 0.38
CYP17A1 P05093 1/20 0.36
CYP1A2 P05177 1/20 0.36
MYC P01106 1/20 0.36
MALT1 Q9UDY8 2/20 0.35
RPS6KA4 O75676 1/20 0.35
PHGDH O43175 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL951100 0.79 RPS6KA5 (0.39) TRPV1HSD11B1RPS6KA5MALT1RPS6KA4
SCHEMBL8498623 0.79 CYP3A4 (0.50) TRPV1HSD11B1RPS6KA5CYP17A1CYP1A2
SCHEMBL12528795 0.79 MYC (0.36) RPS6KA5MYC
SCHEMBL12528652 0.76 TRPV1 (0.42) TRPV1HSD11B1CYP17A1CYP1A2MALT1
SCHEMBL12528751 0.75 EPHX2 (0.48) HSD11B1
SCHEMBL950454 0.75 ALDH1A1 (0.46) HSD11B1RPS6KA5CYP1A2
SCHEMBL12528738 0.75 MYC (0.33) MYC
SCHEMBL8500406 0.74 RPS6KA5 (0.40) TRPV1HSD11B1RPS6KA5MALT1RPS6KA4
SCHEMBL12528531 0.73 TRPV1 (0.40) TRPV1HSD11B1RPS6KA5CYP17A1CYP1A2
SCHEMBL12528693 0.73 TRPV1 (0.40) TRPV1HSD11B1RPS6KA5CYP17A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968573-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-28 US disclosed
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME IKEGAMI HIROSHI 2011-03-24 US disclosed
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME ACHE, H1-2, H1-0 TRPV1 1056/4885HSD11B1 1797/4885RPS6KA5 2425/4885
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT TRPV1 687/4885HSD11B1 651/4885RPS6KA5 3415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.