Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14805255 | 0.85 | TGFBR1 (0.40) | LMNAHPGDMAPK1HSD17B10TSHR | |
| SCHEMBL12546758 | 0.82 | CYP11B1 (0.47) | HPGDMEN1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL21704897 | 0.81 | ESR1 (0.35) | LMNAHPGDMAPK1HSD17B10TSHR | |
| SCHEMBL14805249 | 0.81 | CCR1 (0.42) | LMNAHPGDMAPK1HSD17B10TSHR | |
| SCHEMBL18858084 | 0.80 | DHODH (0.42) | LMNAHPGDMAPK1HSD17B10TSHR | |
| SCHEMBL134622 | 0.80 | DHODH (0.41) | LMNAHPGDMAPK1HSD17B10TSHR | |
| SCHEMBL12546669 | 0.79 | METAP2 (0.37) | LMNAHPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12546627 | 0.79 | METAP2 (0.37) | LMNAHPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12032294 | 0.79 | LMNA (0.42) | LMNAHPGDMAPK1HSD17B10TSHR | |
| SCHEMBL24662781 | 0.79 | GRM5 (0.46) | LMNAHPGDMAPK1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288016-B2 | Fused polycyclic compound and organic light-emitting device using the compound | CANON KABUSHIKI KAISHA (JP) | 2012-10-16 | — | — | US | disclosed |
| US-8288016-B2 | Fused polycyclic compound and organic light-emitting device using the compound | CANON KABUSHIKI KAISHA (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20110127908-A1 | FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2011-06-02 | — | — | US | disclosed |
| US-20110127908-A1 | FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110127908-A1 | FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND | RPS19, RPL19, RNF168 | LMNA 2902/4885HPGD 4041/4885MAPK1 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.