Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.30 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.30 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.30 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.30 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 3/20 | 0.30 |
| ▸ | RAB9A | P51151 | 3/20 | 0.30 |
| ▸ | MGAM | O43451 | 2/20 | 0.30 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.30 |
| ▸ | SI | P14410 | 2/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049842 | 0.84 | PTPN1 (0.44) | MAPTSMN1; SMN2TP53GAATHRB | |
| SCHEMBL73948 | 0.81 | MAPT (0.36) | MAPTSMN1; SMN2TP53GAAKDM4E | |
| SCHEMBL7243970 | 0.80 | PKM (0.37) | MAPTSMN1; SMN2TP53ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL17701156 | 0.80 | MAPT (0.35) | MAPTSMN1; SMN2TP53GAAKDM4E | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL2455715 | 0.80 | ALDH1A1 (0.44) | MAPTSMN1; SMN2TP53KDM4EMEN1 | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL9084433 | 0.78 | ALDH1A1 (0.43) | MAPTSMN1; SMN2TP53KDM4EMEN1 | |
| SCHEMBL3743974 | 0.78 | PARP1 (0.40) | MAPTSMN1; SMN2TP53GAAKDM4E | |
| SCHEMBL8051642 | 0.78 | MAPT (0.45) | MAPTSMN1; SMN2TP53THRBMEN1 | |
| SCHEMBL7555956 | 0.78 | MAPT (0.39) | MAPTSMN1; SMN2TP53KDM4ETHRB | |
| SCHEMBL4031502 | 0.77 | GAA (0.44) | MAPTSMN1; SMN2TP53GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9445601-B2 | Fungicide active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-20 | — | — | US | disclosed |
| US-20160106105-A1 | FUNGICIDE ACTIVE SUBSTANCE COMBINATIONS | BAYER IP GMBH (DE) | 2016-04-21 | — | — | US | disclosed |
| US-9253982-B2 | Fungicide active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-09 | — | — | US | disclosed |
| US-20140364469-A1 | Fungicide Active Substance Combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-12-11 | — | — | US | disclosed |
| US-8846738-B2 | Fungicide active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| US-20140066407-A1 | Fungicide Active Substance Combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-06 | — | — | US | disclosed |
| US-20130296389-A1 | Fungicide Active Substance Combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-07 | — | — | US | disclosed |
| US-20130190371-A1 | Fungicide Active Substance Combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-25 | — | — | US | disclosed |
| US-7956009-B2 | Fungicidal combinations of active substances | BAYER CROPSCIENCE AG (DE) | 2011-06-07 | — | — | US | disclosed |
| US-20090306109-A1 | FUNGICIDE ACTIVE SUBSTANCE COMBINATIONS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364469-A1 | Fungicide Active Substance Combinations | DDT, CYP4X1, CYP51A1 | MAPT 3711/4885SMN1; SMN2 3571/4885TP53 4650/4885 |
| US-20140066407-A1 | Fungicide Active Substance Combinations | DDT, CYP4X1, CYP51A1 | MAPT 3711/4885SMN1; SMN2 3571/4885TP53 4650/4885 |
| US-20160106105-A1 | FUNGICIDE ACTIVE SUBSTANCE COMBINATIONS | DDT, CYP4X1, CYP51A1 | MAPT 3711/4885SMN1; SMN2 3571/4885TP53 4650/4885 |
| US-20130296389-A1 | Fungicide Active Substance Combinations | DDT, CYP4X1, CYP1B1 | MAPT 3594/4885SMN1; SMN2 3445/4885TP53 4640/4885 |
| US-20090306109-A1 | FUNGICIDE ACTIVE SUBSTANCE COMBINATIONS | DDT, CYP4X1, CYP51A1 | MAPT 3711/4885SMN1; SMN2 3571/4885TP53 4650/4885 |
| US-20130190371-A1 | Fungicide Active Substance Combinations | DDT, CYP4X1, CYP1B1 | MAPT 4061/4885SMN1; SMN2 3184/4885TP53 4725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.