SCHEMBL125499

SCHEMBL125499

c1ccc(-[n+]2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
ACHE P22303 5/20 0.34
BCHE P06276 3/20 0.34
ALDH1A1 P00352 2/20 0.33
SLC22A2 O15244 1/20 0.33
SLC22A1 O15245 1/20 0.33
SLC22A3 O75751 1/20 0.33
SLC6A4 P31645 1/20 0.33
HTT P42858 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HDAC8 Q9BY41 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TP53 P04637 1/20 0.32
LMNA P02545 2/20 0.31
TDP1 Q9NUW8 2/20 0.30
BCL2 P10415 1/20 0.30
CA12 O43570 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL2150507 0.97 ACHE (0.37) MAPTNPC1RAB9AACHEBCHE
Fluoride Ion SCHEMBL1502890 0.97 MAPT (0.34) MAPTNPC1RAB9AACHEBCHE
Iodide SCHEMBL1502876 0.97 MAPT (0.34) MAPTNPC1RAB9AACHEBCHE
Ammonia Solution, Strong SCHEMBL4202272 0.97 MAPT (0.34) MAPTNPC1RAB9AACHEBCHE
Bromide SCHEMBL636300 0.97 ACHE (0.37) MAPTNPC1RAB9AACHEBCHE
SCHEMBL28558026 0.97 MAPT (0.34) MAPTNPC1RAB9AACHEBCHE
Hydrochloric Acid SCHEMBL30042005 0.97 MAPT (0.35) MAPTNPC1RAB9AACHEBCHE
SCHEMBL28817308 0.97 MAPT (0.34) MAPTNPC1RAB9AACHEBCHE
Hydrochloric Acid SCHEMBL636092 0.97 MAPT (0.35) MAPTNPC1RAB9AACHEBCHE
SCHEMBL776579 0.90 NPC1 (0.37) MAPTNPC1RAB9AACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 380 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110114438-B Electrochromic compounds and optical articles containing them 依视路国际公司 2022-12-06 CN claimed
CN-113200526-A Method for preparing boron nitride nanosheet by stripping method and boron nitride nanosheet 江南大学 2021-08-03 CN claimed
CN-112323178-A Waterproof antistatic chemical fiber yarn and manufacturing method thereof 防城港盛农磷化有限公司 2021-02-05 CN claimed
US-20100004132-A1 MODIFIED INORGANINC MATERIALS THE UNIVERSITY OF SYDNEY (AU) 2010-01-07 US claimed
US-20090054498-A1 Anhydrous Compositions Useful for Attaining Enhanced Sexual Wellness MCNEIL-PPC, INC. 2009-02-26 US claimed
EP-1006374-B1 Process for producing a resin having a large refractive index MITSUBISHI GAS CHEMICAL CO (JP) 2009-01-07 EP claimed
EP-0453197-B1 Amine derivatives ICI PLC (GB) 1994-06-15 EP claimed
US-4225497-A ACID CATALYSTS FOR IMIDATION RHONE-POULENC INDUSTRIES (FR) 1980-09-30 US claimed
US-20250122316-A1 CURABLE COMPOSITION AND CURED PRODUCT DEXERIALS CORPORATION (JP) 2025-04-17 US disclosed
US-12269782-B2 Coloured fiber cement products and methods for the production thereof SOCIEDAD INDUSTRIAL PIZARREÑO (CO) 2025-04-08 US disclosed
US-12234320-B2 Process for preparing polycarbonate and catalytic system used ENI S.P.A. (IT) 2025-02-25 US disclosed
US-20250004378-A1 Pattern Forming Method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-01-02 US disclosed
CN-119183383-A Programmable recruitment of transcription factors to endogenous genes 思研(SRI)国际顾问与咨询公司 2024-12-24 CN disclosed
EP-4474911-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-12-11 EP disclosed
EP-0953613-A2 Ink, ink-jet recording method using the same, and photopolymerization initiator CANON KABUSHIKI KAISHA (JP) 1999-11-03 EP disclosed
US-5202042-A Carboxylic acid salt of cationic nitrogen-containing heterocyclic compound in aprotic solvent or solvent mixture containing polyol NIPPON CHEMI-CON CORPORATION (JP) 1993-04-13 US disclosed
US-4692450-A Phenyl-pyrimidinium, thiazolium or imidazolium salts and use in inhibiting intestinal resorption of cholesterol and bile salts HOFFMANN-LA ROCHE INC. (US) 1987-09-08 US disclosed
US-4675328-A CHOLESTROL AND BILE SALTS HOFFMANN-LAROCHE INC. (US) 1987-06-23 US disclosed
US-4675328-A CHOLESTROL AND BILE SALTS HOFFMANN-LAROCHE INC. (US) 1987-06-23 US disclosed
US-4225497-A ACID CATALYSTS FOR IMIDATION RHONE-POULENC INDUSTRIES (FR) 1980-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12234320-B2 Process for preparing polycarbonate and catalytic system used F9, TAF9, TAF11 MAPT 3491/4885NPC1 2916/4885RAB9A 2476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.