Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 9/20 | 0.37 |
| ▸ | BCHE | P06276 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125499 | 0.97 | MAPT (0.35) | ACHEBCHEMEN1KMT2AMAPT | |
| SCHEMBL28558026 | 0.94 | MAPT (0.34) | ACHEBCHEMEN1KMT2AMAPT | |
| SCHEMBL28817308 | 0.94 | MAPT (0.34) | ACHEBCHEMEN1KMT2AMAPT | |
| Iodide SCHEMBL1502876 | 0.94 | MAPT (0.34) | ACHEBCHEMEN1KMT2AMAPT | |
| Water SCHEMBL2150507 | 0.94 | ACHE (0.37) | ACHEBCHEMEN1KMT2AMAPT | |
| Ammonia Solution, Strong SCHEMBL4202272 | 0.94 | MAPT (0.34) | ACHEBCHEMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL30042005 | 0.94 | MAPT (0.35) | ACHEBCHEMEN1KMT2AMAPT | |
| Fluoride Ion SCHEMBL1502890 | 0.94 | MAPT (0.34) | ACHEBCHEMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL636092 | 0.94 | MAPT (0.35) | ACHEBCHEMEN1KMT2AMAPT | |
| SCHEMBL776579 | 0.87 | NPC1 (0.37) | ACHEMAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006374-B1 | Process for producing a resin having a large refractive index | MITSUBISHI GAS CHEMICAL CO (JP) | 2009-01-07 | — | — | EP | claimed |
| WO-2024146848-A1 | CURABLE MATERIALS BASED ON CYCLIC THIOETHER COMPOUNDS, AND USES THEREOF | DELO INDUSTRIE KLEBSTOFFE GMBH & CO. KGAA (DE) | 2024-07-11 | — | — | WO | disclosed |
| EP-2735581-B1 | COMPOSITION AND POLYMER | ASAHI CHEMICAL IND (JP) | 2021-07-14 | — | — | EP | disclosed |
| EP-2169028-B1 | Material for organic electroluminescent devices and organic electroluminescent devices made by using the same | IDEMITSU KOSAN CO (JP) | 2018-11-21 | — | — | EP | disclosed |
| EP-2799455-B1 | Resin composition for optical member and optical member obtained from the same | MITSUBISHI GAS CHEMICAL CO (JP) | 2018-03-28 | — | — | EP | disclosed |
| EP-2295484-B1 | POLYMERIZABLE COMPOSITION FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYTHIOURETHANE OPTICAL MATERIAL OBTAINED FROM SAME POLYMERIZABLE COMPOSITION, AND POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL | MITSUI CHEMICALS INC (JP) | 2018-01-17 | — | — | EP | disclosed |
| US-9738757-B2 | Composition and polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2017-08-22 | — | — | US | disclosed |
| CN-104918931-B | Epoxy and thio epoxy functionalized polymerisable compound and the method that optical goods are prepared by it | PPG工业俄亥俄公司 | 2017-08-15 | — | — | CN | disclosed |
| EP-2700636-B1 | PROCESS FOR PREPARING EPISULFIDE COMPOUNDS | ASAHI CHEMICAL IND (JP) | 2017-08-02 | — | — | EP | disclosed |
| US-9469731-B2 | Epoxide and thioepoxide functional, polymerizable composition and methods of preparing optical articles therefrom | PPG INDUSTRIES OHIO, INC. (US) | 2016-10-18 | — | — | US | disclosed |
| US-6534589-B1 | Catalytic curing and polymerization of episulfide compound in presence of phenolic compound | MITSUBISHI GAS CHEMICAL COMPANY INC. (JP) | 2003-03-18 | — | — | US | disclosed |
| US-6531532-B1 | Optical apparatus formed by curing sulfides, intermetallics and 1,2-bis/-epithiopropylthio/ethane to form lenses having large refractive index and optical distortion | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-03-11 | — | — | US | disclosed |
| US-6472495-B1 | RESIN PRODUCED BY CURING THE COMPOSITION BY POLYMERIZATION HAS AN EXCELLENT IMPACT RESISTANCE AND OPTICAL PROPERTIES, AND IS SUITABLE AS AN OPTICAL MATERIAL. POLYMERS WITH SULFIDE, SELINIUM AND TELLURIUM | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-10-29 | — | — | US | disclosed |
| EP-1099721-A1 | Composition for producing resin | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2001-05-16 | — | — | EP | disclosed |
| US-6201061-B1 | CURING A RESIN FOR OPTICAL USE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2001-03-13 | — | — | US | disclosed |
| EP-1046931-A2 | Composition for optical materials | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2000-10-25 | — | — | EP | disclosed |
| US-6130307-A | POLY(THIO)URETHANES | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-1006374-A2 | Process for producing a resin having a large refractive index | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2000-06-07 | — | — | EP | disclosed |
| EP-0950905-A2 | Process for producing a novel resin for optical materials having excellent color tone and transparency | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1999-10-20 | — | — | EP | disclosed |
| EP-0936233-A2 | Composition for a resin | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1999-08-18 | — | — | EP | disclosed |