Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL636092 | 1.00 | MAPT (0.35) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL125499 | 0.97 | MAPT (0.35) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28558026 | 0.94 | MAPT (0.34) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| Water SCHEMBL2150507 | 0.94 | ACHE (0.37) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| Fluoride Ion SCHEMBL1502890 | 0.94 | MAPT (0.34) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL4202272 | 0.94 | MAPT (0.34) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| Bromide SCHEMBL636300 | 0.94 | ACHE (0.37) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28817308 | 0.94 | MAPT (0.34) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| Iodide SCHEMBL1502876 | 0.94 | MAPT (0.34) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL776579 | 0.87 | NPC1 (0.37) | MAPTHTTNPC1RAB9AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115207505-A | Application of metal-chlorine bridge dimer | 广东光华科技股份有限公司 | 2022-10-18 | — | — | CN | disclosed |