Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30042005 | 1.00 | MAPT (0.35) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL125499 | 0.97 | MAPT (0.35) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28558026 | 0.94 | MAPT (0.34) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| Water SCHEMBL2150507 | 0.94 | ACHE (0.37) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| Fluoride Ion SCHEMBL1502890 | 0.94 | MAPT (0.34) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL4202272 | 0.94 | MAPT (0.34) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| Bromide SCHEMBL636300 | 0.94 | ACHE (0.37) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28817308 | 0.94 | MAPT (0.34) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| Iodide SCHEMBL1502876 | 0.94 | MAPT (0.34) | MAPTHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL776579 | 0.87 | NPC1 (0.37) | MAPTHTTNPC1RAB9AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113567380-A | Benzyl chloride pyridinium derivative used as PH indicator and synthetic method thereof | 湖北科技学院 | 2021-10-29 | — | — | CN | claimed |
| CN-113484317-A | Method for preparing PH test paper through benzyl chloride pyridinium derivative | 湖北科技学院 | 2021-10-08 | — | — | CN | claimed |
| US-11982612-B2 | Systems and methods for color-scalable flow cytometry with Raman tags | BAYSPEC, INC. (US) | 2024-05-14 | — | — | US | disclosed |
| US-20230333001-A1 | SYSTEMS AND METHODS FOR COLOR-SCALABLE FLOW CYTOMETRY WITH RAMAN TAGS | BAYSPEC, INC. | 2023-10-19 | — | — | US | disclosed |
| CN-113557313-A | Method and apparatus for producing aluminum material | 株式会社UACJ | 2021-10-26 | — | — | CN | disclosed |
| EP-2295484-B1 | POLYMERIZABLE COMPOSITION FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYTHIOURETHANE OPTICAL MATERIAL OBTAINED FROM SAME POLYMERIZABLE COMPOSITION, AND POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL | MITSUI CHEMICALS INC (JP) | 2018-01-17 | — | — | EP | disclosed |
| US-9290656-B2 | Polymerizable composition for polythiourethane optical material | MITSUI CHEMICALS, INC. (JP) | 2016-03-22 | — | — | US | disclosed |
| US-20160074856-A1 | RECOVERY METHOD AND REUSE METHOD OF OXO ACID CATALYST | DAICEL CORPORATION (JP) | 2016-03-17 | — | — | US | disclosed |
| EP-2990110-A1 | RECOVERY METHOD AND REUSE METHOD OF OXO ACID CATALYST | Daicel Corporation (JP) | 2016-03-02 | — | — | EP | disclosed |
| US-20140349969-A1 | COMPOUNDS AND METHODS FOR TREATING PAIN | AKRON MOLECULES AG (AT) | 2014-11-27 | — | — | US | disclosed |
| US-8642718-B2 | Curable composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-02-04 | — | — | US | disclosed |
| US-20040024165-A1 | Composition for optical material | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2004-02-05 | — | — | US | disclosed |
| EP-1326095-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-07-09 | — | — | EP | disclosed |
| EP-1319966-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-06-18 | — | — | EP | disclosed |
| EP-1316819-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-06-04 | — | — | EP | disclosed |
| EP-0453197-B1 | Amine derivatives | ICI PLC (GB) | 1994-06-15 | — | — | EP | disclosed |
| EP-0119831-B1 | HEAT BLEACHABLE DYE SYSTEMS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-01-07 | — | — | EP | disclosed |
| US-4594312-A | Photothermographic medium | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-06-10 | — | — | US | disclosed |
| EP-0119831-A2 | Heat bleachable dye systems | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4108882-A | QUATERNARY AMMONIUM HALIDE CATALYST | DOW CORNING CORPORATION (US) | 1978-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140349969-A1 | COMPOUNDS AND METHODS FOR TREATING PAIN | TRPV1, ACHE, OPRL1 | ACHE 2/4885MAPT 898/4885HTT 384/4885 |
| US-20160074856-A1 | RECOVERY METHOD AND REUSE METHOD OF OXO ACID CATALYST | HAO2, HAO1, AOX1 | ACHE 177/4885MAPT 4165/4885HTT 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.