Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12551594 | 0.95 | L3MBTL1 (0.52) | L3MBTL1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL12551595 | 0.87 | L3MBTL1 (0.43) | L3MBTL1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL12551593 | 0.85 | GP6 (0.46) | L3MBTL1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL371042 | 0.84 | L3MBTL1 (0.74) | L3MBTL1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL12551592 | 0.82 | GPR55 (0.44) | L3MBTL1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL12551610 | 0.82 | MAPK1 (0.46) | L3MBTL1NPC1RAB9AMAPK1MEN1 | |
| SCHEMBL12551661 | 0.82 | L3MBTL1 (0.44) | L3MBTL1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL11978708 | 0.81 | L3MBTL1 (0.58) | L3MBTL1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL12951259 | 0.81 | DPP4 (0.53) | L3MBTL1ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL28401894 | 0.81 | L3MBTL1 (0.52) | L3MBTL1ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160240782-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2016-08-18 | — | — | US | disclosed |
| US-20160240782-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2016-08-18 | — | — | US | disclosed |
| EP-2307520-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2015-11-11 | — | — | EP | disclosed |
| US-20110140043-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2011-06-16 | — | — | US | disclosed |
| US-20110140043-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2011-06-16 | — | — | US | disclosed |
| WO-2010006680-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110140043-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | L1CAM, SLCO4C1, GJA1 | L3MBTL1 2095/4885ADORA2A 3304/4885ADORA1 2092/4885 |
| US-20160240782-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | L1CAM, SLCO4C1, GJA1 | L3MBTL1 2095/4885ADORA2A 3304/4885ADORA1 2092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.