Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 17/20 | 1.00 |
| ▸ | PRKDC | P78527 | 17/20 | 1.00 |
| ▸ | PIK3CA | P42336 | 15/20 | 1.00 |
| ▸ | PIK3CB | P42338 | 15/20 | 1.00 |
| ▸ | PIK3CG | P48736 | 15/20 | 1.00 |
| ▸ | SRC | P12931 | 9/20 | 1.00 |
| ▸ | ABL1 | P00519 | 7/20 | 1.00 |
| ▸ | EGFR | P00533 | 5/20 | 1.00 |
| ▸ | HCK | P08631 | 5/20 | 1.00 |
| ▸ | KDR | P35968 | 5/20 | 1.00 |
| ▸ | MTOR | P42345 | 5/20 | 1.00 |
| ▸ | EPHB4 | P54760 | 5/20 | 1.00 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.67 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.67 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130611 | 0.87 | PIK3CD (0.77) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL129615 | 0.86 | SRC (0.79) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL12608279 | 0.84 | SRC (1.00) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL1964558 | 0.84 | SRC (1.00) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL21048473 | 0.84 | PIK3CD (1.00) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL14574867 | 0.84 | SRC (1.00) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29390926 | 0.84 | SRC (1.00) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29390060 | 0.84 | SRC (1.00) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30385963 | 0.84 | PIK3CD (1.00) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29391405 | 0.84 | SRC (1.00) | PIK3CDPRKDCPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-9512125-B2 | Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-12-06 | — | — | US | disclosed |
| US-9512125-B2 | Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-12-06 | — | — | US | disclosed |
| US-20110144134-A1 | Anti-Inflammatory Pyrazolopyrimndines | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-16 | — | — | US | disclosed |
| US-20110144134-A1 | Anti-Inflammatory Pyrazolopyrimndines | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-16 | — | — | US | disclosed |
| US-20090124638-A1 | ANTI-INFLAMMATORY PYRAZOLOPYRIMIDINES | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-05-14 | — | — | US | disclosed |
| US-20090124638-A1 | ANTI-INFLAMMATORY PYRAZOLOPYRIMIDINES | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144134-A1 | Anti-Inflammatory Pyrazolopyrimndines | TSLP, NLRP3, IL1B | PIK3CD 3674/4885PRKDC 1687/4885PIK3CA 3812/4885 |
| US-20090124638-A1 | ANTI-INFLAMMATORY PYRAZOLOPYRIMIDINES | TNF, TSLP, IL1B | PIK3CD 3413/4885PRKDC 2166/4885PIK3CA 2924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.