Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9991927 | 0.90 | CDK2 (0.39) | CCR6L3MBTL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL15203404 | 0.85 | L3MBTL1 (0.42) | CCR6L3MBTL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL9989458 | 0.83 | L3MBTL1 (0.41) | CCR6L3MBTL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL1933897 | 0.82 | KDM4E (0.40) | CCR6L3MBTL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL23061211 | 0.81 | NOD2 (0.40) | CCR6L3MBTL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL30368521 | 0.81 | PDE4B (0.40) | ALDH1A1LMNAEPHX2PDE4BHTR6 | |
| SCHEMBL2273831 | 0.81 | PDE4B (0.40) | ALDH1A1LMNAEPHX2PDE4BHTR6 | |
| SCHEMBL20706502 | 0.80 | L3MBTL1 (0.39) | CCR6L3MBTL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL1934468 | 0.80 | ALDH1A1 (0.39) | CCR6L3MBTL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL12555217 | 0.80 | AURKA (0.36) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011068881-A1 | NOVEL TRICYCLIC COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-09 | — | — | WO | disclosed |