Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | CCR6 | P51684 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1933897 | 0.90 | KDM4E (0.40) | L3MBTL1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL23061211 | 0.89 | NOD2 (0.40) | L3MBTL1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL1935252 | 0.87 | ALDH1A1 (0.36) | L3MBTL1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL1935255 | 0.87 | ALDH1A1 (0.36) | L3MBTL1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL28917554 | 0.87 | ALDH1A1 (0.36) | L3MBTL1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL15203404 | 0.87 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL9989458 | 0.85 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL9991927 | 0.83 | CDK2 (0.39) | L3MBTL1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL1934468 | 0.83 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL12555136 | 0.80 | CCR6 (0.37) | L3MBTL1ALDH1A1CYP3A4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE47221-E1 | Tricyclic compounds | ABBVIE INC. (US) | 2019-02-05 | — | — | US | disclosed |