Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 6/20 | 0.42 |
| ▸ | SSTR2 | P30874 | 6/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 6/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 6/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 6/20 | 0.42 |
| ▸ | GJB2 | P29033 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16160491 | 1.00 | SSTR1 (0.42) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL16627224 | 1.00 | SSTR1 (0.42) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL16160558 | 1.00 | SSTR1 (0.42) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL10314526 | 1.00 | SSTR1 (0.42) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL16160541 | 1.00 | SSTR1 (0.42) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL17993804 | 0.99 | SSTR1 (0.40) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL16160570 | 0.93 | SSTR4 (0.47) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL16160565 | 0.93 | SSTR4 (0.47) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL17755541 | 0.89 | SSTR1 (0.33) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL10292898 | 0.89 | GJB2 (0.36) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170029454-A1 | NKT CELL LIGANDS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-02-02 | — | — | US | disclosed |
| US-9422325-B2 | Glycosylation reactions using phenyl(trifluoroethyl)iodonium salts | TRUSTEES OF TUFTS COLLEGE (US) | 2016-08-23 | — | — | US | disclosed |
| US-9181293-B2 | Method for the synthesis of aspalathin and analogues thereof | SOUTH AFRICAN MEDICAL RESEARCH COUNCIL (ZA) | 2015-11-10 | — | — | US | disclosed |
| US-20150099870-A1 | Glycosylation Reactions Using Phenyl(trifluoroethyl)iodonium Salts | TRUSTEES OF TUFTS COLLEGE | 2015-04-09 | — | — | US | disclosed |
| US-20130018182-A1 | Method for the Synthesis of Aspalathin and Analogues Thereof | SOUTH AFRICAN MEDICAL RESEARCH COUNCIL (ZA) | 2013-01-17 | — | — | US | disclosed |
| WO-2011064726-A1 | METHOD FOR THE SYNTHESIS OF ASPALATHIN AND ANALOGUES THEREOF | SOUTH AFRICAN MEDICAL RESEARCH COUNCIL (ZA) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099870-A1 | Glycosylation Reactions Using Phenyl(trifluoroethyl)iodonium Salts | UGGT1, OGA, GPI | SSTR1 613/4885SSTR2 1282/4885SSTR4 588/4885 |
| US-20170029454-A1 | NKT CELL LIGANDS AND METHODS OF USE | PBK, CD69, NFATC1 | SSTR1 2583/4885SSTR2 3273/4885SSTR4 3172/4885 |
| US-20130018182-A1 | Method for the Synthesis of Aspalathin and Analogues Thereof | ASPH, C9, ALDH3A1 | SSTR1 3639/4885SSTR2 4160/4885SSTR4 3971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.