Indene

Indene

SCHEMBL1255740

C1=Cc2ccccc2C1.C=C(CC)C(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
KDM4E B2RXH2 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HTT P42858 1/20 0.33
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HRH1 P35367 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
EGFR P00533 2/20 0.31
ALDH1A1 P00352 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
MAPT P10636 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
HSD17B3 P37058 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indene SCHEMBL31277557 0.85 CYP2D6 (0.45) CYP2D6CYP2C19CA1CA2KDM4E
Indene SCHEMBL6273661 0.85 CYP2D6 (0.45) CYP2D6CYP2C19CA1CA2KDM4E
Indene SCHEMBL2769732 0.84 CYP2D6 (0.53) CYP2D6CYP2C19CA1CA2KDM4E
Indene SCHEMBL27975138 0.82 CYP2D6 (0.42) CYP2D6CYP2C19CA1CA2KDM4E
Indene SCHEMBL29746662 0.80 CYP2D6 (0.51) CYP2D6CYP2C19CA1CA2CES2
Indene SCHEMBL89373 0.80 CYP2D6 (0.51) CYP2D6CYP2C19CA1CA2CES2
Indene SCHEMBL6268710 0.80 CYP2D6 (0.39) CYP2D6CYP2C19CA1CA2KDM4E
Indene SCHEMBL30959780 0.80 CA2 (0.47) CYP2D6CYP2C19CA1CA2CES2
Indene SCHEMBL6700608 0.80 CA2 (0.47) CYP2D6CYP2C19CA1CA2CES2
Indene SCHEMBL28769797 0.79 CYP2D6 (0.50) CYP2D6CYP2C19CA1CA2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8470448-B2 Acryl resin containing film, polarizing plate by use thereof and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2013-06-25 US disclosed
US-8168702-B2 Acrylic-resin-containing film, polarizing plate and liquid crystal display device using the same KONICA MINOLTA OPTO INC. (JP) 2012-05-01 US disclosed
US-8158218-B2 Process for producing optical film, optical film, polarizer, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-04-17 US disclosed
US-20110033640-A1 PROCESS FOR PRODUCING OPTICAL FILM, OPTICAL FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2011-02-10 US disclosed
US-20100292368-A1 ACRYLIC-RESIN-CONTAINING FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME KONICA MINOLTA OPTO, INC (JP) 2010-11-18 US disclosed
US-20100291376-A1 ACRYL RESIN CONTAINING FILM, POLARIZING PLATE BY USE THEREOF AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO., INC. (JP) 2010-11-18 US disclosed