SCHEMBL125625

SCHEMBL125625

NNc1cccc(C(F)(F)F)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
IDO1 P14902 1/20 0.61
TSHR P16473 1/20 0.59
MAPK1 P28482 1/20 0.59
MAPT P10636 5/20 0.56
GAA P10253 2/20 0.56
RAB9A P51151 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
NPSR1 Q6W5P4 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
IDH2 P48735 2/20 0.53
MEN1 O00255 2/20 0.53
HTT P42858 2/20 0.53
KMT2A Q03164 2/20 0.53
KIF11 P52732 2/20 0.51
RAPGEF4 Q8WZA2 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
LMNA P02545 1/20 0.50
PKM P14618 1/20 0.50
CA12 O43570 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1309809 0.98 ALDH1A1 (0.59) ALDH1A1IDO1TSHRMAPK1MAPT
Water SCHEMBL14966111 0.98 ALDH1A1 (0.59) ALDH1A1IDO1TSHRMAPK1MAPT
Bromide SCHEMBL20984634 0.98 ALDH1A1 (0.59) ALDH1A1IDO1TSHRMAPK1MAPT
Oxalic Acid SCHEMBL20984526 0.89 ALDH1A1 (0.64) ALDH1A1IDO1MAPTGAARAB9A
Sulfuric Acid SCHEMBL20984653 0.89 ALDH1A1 (0.59) ALDH1A1IDO1MAPK1MAPTGAA
Phosphoric Acid SCHEMBL20984816 0.89 CA12 (0.62) ALDH1A1IDO1TSHRMAPTGAA
Nitric Acid SCHEMBL20984560 0.86 ALDH1A1 (0.56) ALDH1A1IDO1MAPTGAARAB9A
Tert-Butyl Formate SCHEMBL27996984 0.82 ALDH1A1 (0.49) ALDH1A1IDO1MAPTGAARAB9A
SCHEMBL394991 0.82 KIF11 (0.70) ALDH1A1MAPK1MAPTGAARAB9A
SCHEMBL2925587 0.82 MAPT (0.58) ALDH1A1IDO1TSHRMAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118930487-A 1,3, 5-Trisubstituted pyrazole compound and preparation method thereof 赣南师范大学 2024-11-12 CN claimed
CN-110483400-A A kind of preparation method of pyrazole derivatives SHANGHAI INST TECH 2019-11-22 CN claimed
CN-106554770-B A kind of triazole derivative metal-ion fluorescent probe and its preparation method and application 杭州杜易科技有限公司 2018-10-19 CN claimed
EP-3174852-B1 ARYLHYDRAZIDES CONTAINING A 2-PYRIDONE MOIETY AS SELECTIVE ANTIBACTERIAL AGENTS ABAC THERAPEUTICS S L (ES) 2018-07-18 EP claimed
US-4531963-A Promoting germination of oil seeds THE UPJOHN COMPANY (US) 1985-07-30 US claimed
EP-0025692-B1 QUINONE DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1982-12-01 EP claimed
EP-0025692-A1 Quinone derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1981-03-25 EP claimed
US-20260118757-A1 RADIATION-SENSITIVE RESIST COMPOSITION AND PATTERN FORMATION METHOD USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-04-30 US disclosed
CN-118930487-A 1,3, 5-Trisubstituted pyrazole compound and preparation method thereof 赣南师范大学 2024-11-12 CN disclosed
CN-118026884-A Synthesis method of hydroazobenzene and hydroazobenzene 温州大学新材料与产业技术研究院 2024-05-14 CN disclosed
CN-114292234-B Preparation method of pyrazole derivative 南方海洋科学与工程广东省实验室(湛江) 2024-05-14 CN disclosed
US-20230146233-A1 A CLASS OF POLYCYCLIC COMPOUNDS INHIBITING RNA HELICASE DHX33 AND THE APPLICATION THEREOF SHENZHEN KEYE LIFE TECHNOLOGIES, CO., LTD (CN) 2023-05-11 US disclosed
US-20230146233-A1 A CLASS OF POLYCYCLIC COMPOUNDS INHIBITING RNA HELICASE DHX33 AND THE APPLICATION THEREOF SHENZHEN KEYE LIFE TECHNOLOGIES, CO., LTD (CN) 2023-05-11 US disclosed
EP-0002065-A1 Methyladamantyl hydrazines, their pharmaceutically acceptable salts and pharmaceutical compositions containing them Teva Pharmaceutical Industries Limited (IL) 1979-05-30 EP disclosed
US-4155997-A INSECTICIDES, MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-05-22 US disclosed
US-4146721-A ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1979-03-27 US disclosed
US-4045169-A FLUORESCENT DYES HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-30 US disclosed
US-4005076-A ANTIBIOTICS GRUPPO LEPETIT S.P.A. (IT) 1977-01-25 US disclosed
US-3957815-A 3-[3',4'-Dichloro-6'-alkyl-phenyl]-Δ2 -pyrazoline derivatives and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed
US-3947513-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118757-A1 RADIATION-SENSITIVE RESIST COMPOSITION AND PATTERN FORMATION METHOD USING THE SAME SLC39A14, HCN4, SLC11A2 ALDH1A1 4370/4885IDO1 3888/4885TSHR 897/4885
US-20230146233-A1 A CLASS OF POLYCYCLIC COMPOUNDS INHIBITING RNA HELICASE DHX33 AND THE APPLICATION THEREOF DHX36, DDX21, DDX3X ALDH1A1 1988/4885IDO1 4261/4885TSHR 4492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.