Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 6/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12563150 | 0.80 | MEN1 (0.82) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL12563195 | 0.77 | SMN1; SMN2 (1.00) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL4669644 | 0.76 | MEN1 (0.97) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL2876692 | 0.66 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL6545369 | 0.66 | MAPT (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL16306321 | 0.63 | MEN1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL309794 | 0.59 | MAPT (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL25873873 | 0.59 | MEN1 (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL21910776 | 0.59 | PDK2 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL2324023 | 0.59 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170216332-A1 | SMALL MOLECULE ANTI-SCARRING AGENTS | UNIVERSITY OF ROCHESTER (US) | 2017-08-03 | — | — | US | disclosed |
| US-20110152251-A1 | COMPOUNDS FOR MODULATING TLR2 | UNIVERSITY OF MASSACHUSETTS (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216332-A1 | SMALL MOLECULE ANTI-SCARRING AGENTS | COLGALT1, MMP1, FIBP | ALDH1A1 970/4885MEN1 4453/4885KMT2A 3498/4885 |
| US-20110152251-A1 | COMPOUNDS FOR MODULATING TLR2 | TLR2, TLR3, NFKBIA | ALDH1A1 4294/4885MEN1 4791/4885KMT2A 2989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.