Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 6/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | BRD4 | O60885 | 5/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060192 | 0.75 | MEN1 (1.00) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL6545194 | 0.74 | MAPT (1.00) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL6545099 | 0.71 | KDM4E (0.50) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL29044241 | 0.70 | GAA (0.47) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL7750822 | 0.69 | KDM4E (0.50) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL12463182 | 0.68 | L3MBTL1 (0.66) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL12462878 | 0.68 | L3MBTL1 (0.66) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL2279059 | 0.68 | GAA (0.51) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL16268747 | 0.68 | GAA (0.63) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL9629698 | 0.66 | CREBBP (0.64) | MEN1KMT2AGAAALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027055-B1 | 3-CARBOALKOXY-2,3-DIHYDRO-1H-PHENOTHIAZIN-4(10H)-ONE DERIVATIVES | UNIV HOWARD (US) | 2004-01-07 | — | — | EP | disclosed |
| EP-1027055-A4 | 3-CARBOALKOXY-2,3-DIHYDRO-1H-PHENOTHIAZIN-4(10H)-ONE DERIVATIVES | UNIV HOWARD (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-1027055-A1 | 3-CARBOALKOXY-2,3-DIHYDRO-1H-PHENOTHIAZIN-4(10H)-ONE DERIVATIVES | HOWARD UNIVERSITY (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5994349-A | ANTIEPILEPTIC AGENTS | HOWARD UNIVERSITY (US) | 1999-11-30 | — | — | US | disclosed |
| WO-1999021560-A1 | 3-CARBOALKOXY-2,3-DIHYDRO-1H-PHENOTHIAZIN-4[10H]-ONE DERIVATIVES | HOWARD UNIVERSITY (US) | 1999-05-06 | — | — | WO | disclosed |