SCHEMBL125651

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28383136	0.86	HTT (0.68)	HTTLMNASMN1; SMN2GAAPRSS1
	SCHEMBL127662	0.86	HTT (0.82)	HTTLMNASMN1; SMN2GAAKEAP1
	SCHEMBL903426	0.86	HTT (0.63)	HTTLMNASMN1; SMN2GAAPRSS1
	SCHEMBL3295121	0.85	HTT (0.62)	HTTLMNASMN1; SMN2GAAPRSS1
	SCHEMBL2516832	0.85	HTT (0.66)	HTTLMNASMN1; SMN2GAAPRSS1
	Hydrochloric Acid SCHEMBL7400993	0.84	HTT (0.79)	HTTLMNASMN1; SMN2GAAKEAP1
	SCHEMBL127919	0.84	HTT (0.54)	HTTLMNASMN1; SMN2CASP1GAA
	Glycolic Acid SCHEMBL27895348	0.83	HTT (0.60)	HTTLMNASMN1; SMN2GAAPRSS1
	SCHEMBL5408406	0.82	HTT (0.58)	HTTLMNASMN1; SMN2GAAPRSS1
	SCHEMBL13055383	0.82	LMNA (0.80)	HTTLMNASMN1; SMN2GAAKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.