SCHEMBL1256533

SCHEMBL1256533

CC(=O)c1ccnc(C(C)=O)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
SORD Q00796 3/20 0.45
KDM4E B2RXH2 5/20 0.36
KDM5A P29375 2/20 0.36
KDM3A Q9Y4C1 2/20 0.36
JMJD1C Q15652 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
KMO O15229 4/20 0.33
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
MAPT P10636 2/20 0.32
KDM6B O15054 1/20 0.32
TET3 O43151 1/20 0.32
KDM4A O75164 1/20 0.32
BBOX1 O75936 1/20 0.32
KDM5C P41229 1/20 0.32
ASPH Q12797 1/20 0.32
KDM4D Q6B0I6 1/20 0.32
TET2 Q6N021 1/20 0.32
ALKBH5 Q6P6C2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21935430 0.86 ALDH1A1 (0.42) ALDH1A1SORDKDM4EKDM5AKDM3A
SCHEMBL882664 0.78 ALDH1A1 (0.47) ALDH1A1KDM4EKDM5AKDM3AJMJD1C
SCHEMBL3590598 0.78 ALDH1A1 (0.47) ALDH1A1SORDKDM4EKDM5AKDM3A
SCHEMBL3590602 0.78 ALDH1A1 (0.47) ALDH1A1SORDKDM4EKDM5AKDM3A
SCHEMBL882969 0.78 SORD (0.45) ALDH1A1SORDKDM4ESMN1; SMN2KMO
SCHEMBL8159378 0.77 SORD (0.44) ALDH1A1SORDSMN1; SMN2KMOPDE3B
SCHEMBL2012751 0.77 ALDH1A1 (0.45) ALDH1A1KDM4EKDM5AKDM3AJMJD1C
Hydrochloric Acid SCHEMBL8170615 0.77 SORD (0.44) ALDH1A1SORDKDM4ESMN1; SMN2KMO
SCHEMBL4761994 0.77 ALDH1A1 (0.45) ALDH1A1SORDKDM4EKDM5AKDM3A
SCHEMBL16421042 0.77 SORD (0.44) ALDH1A1SORDKDM4EKMOMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3235888-A2 COMPOSITIONS FOR PRESSURE-SENSITIVE ADHESIVE AND METHOD FOR PRODUCTION THEREOF tesa SE (DE) 2017-10-25 EP disclosed
US-20150148444-A1 PRESSURE-SENSITIVE ADHESIVES AND PROCESS FOR PREPARING THEM TESA SE (DE) 2015-05-28 US disclosed
US-8969479-B2 Pressure-sensitive adhesives and process for preparing them TESA SE (DE) 2015-03-03 US disclosed
US-8536276-B2 Pressure-sensitive adhesives and process for preparing them TESA SE (DE) 2013-09-17 US disclosed
US-8372932-B2 Pressure-senstive adhesives and process for preparing them TESA SE (DE) 2013-02-12 US disclosed
EP-2143773-B1 Adhesive masses and method for their manufacture TESA SE (DE) 2011-04-27 EP disclosed
US-20110039970-A1 PRESSURE-SENSTIVE ADHESIVES AND PROCESS FOR PREPARING THEM TESA SE (DE) 2011-02-17 US disclosed
EP-1791885-B1 METHOD FOR PRODUCING CONTACT ADHESIVE MASSES CONTAINING ACRYLIC TESA SE (DE) 2010-03-17 EP disclosed
US-20100010112-A1 PRESSURE-SENSITIVE ADHESIVES AND PROCESS FOR PREPARING THEM TESA AG (DE) 2010-01-14 US disclosed
US-20100010170-A1 PRESSURE-SENSITIVE ADHESIVES AND PROCESS FOR PREPARING THEM TESA AG (DE) 2010-01-14 US disclosed
EP-2143773-A1 Adhesive masses and method for their manufacture tesa SE (DE) 2010-01-13 EP disclosed
EP-2143774-A2 Adhesive masses and method for their manufacture Tesa AG (DE) 2010-01-13 EP disclosed
US-7605212-B2 Method for producing contact adhesive masses containing acrylic TESA SE (DE) 2009-10-20 US disclosed
EP-1883686-A2 PRESSURE-SENSITIVE ADHESIVE MASS AND METHOD FOR THE PRODUCTION THEREOF tesa AG (DE) 2008-02-06 EP disclosed
US-20070282064-A1 Method for Producing Contact Adhesive Masses Containing Acrylic TESA AG (DE) 2007-12-06 US disclosed
EP-1791885-A1 METHOD FOR PRODUCING CONTACT ADHESIVE MASSES CONTAINING ACRYLIC tesa AG (DE) 2007-06-06 EP disclosed
US-20060257650-A1 Pressure-sensitive adhesives and process for preparing them TESA AKTIENGESELLSCHAFT (DE) 2006-11-16 US disclosed
WO-2006120136-A2 PRESSURE-SENSITIVE ADHESIVE MASS AND METHOD FOR THE PRODUCTION THEREOF TESA AG (DE) 2006-11-16 WO disclosed
WO-2006027386-A1 METHOD FOR PRODUCING CONTACT ADHESIVE MASSES CONTAINING ACRYLIC TESA AG (DE) 2006-03-16 WO disclosed