SCHEMBL125728

SCHEMBL125728

c1ccc(-c2cccc3c2oc2ccccc23)c(-c2c3ccccc3c(-c3cccc4ccccc34)c3ccccc23)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.51
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
PRKDC P78527 5/20 0.43
PIK3CD O00329 2/20 0.43
PIK3CB P42338 2/20 0.43
NTRK1 P04629 1/20 0.37
PLK3 Q9H4B4 1/20 0.37
GGPS1 O95749 1/20 0.37
ATM Q13315 1/20 0.37
AHR P35869 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
MAOA P21397 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL126787 0.97 ALOX5 (0.51) ALOX5KDM4EALDH1A1GAAMAPT
SCHEMBL126624 0.94 ALOX5 (0.48) ALOX5KDM4EALDH1A1GAAMAPT
SCHEMBL125837 0.93 ALOX5 (0.50) ALOX5KDM4EALDH1A1GAAMAPT
SCHEMBL126542 0.92 ALOX5 (0.58) ALOX5KDM4EALDH1A1MAPTHPGD
SCHEMBL12577399 0.92 ALOX5 (0.45) ALOX5KDM4EALDH1A1GAAMAPT
SCHEMBL20334253 0.91 ALOX5 (0.52) ALOX5KDM4EALDH1A1GAAMAPT
SCHEMBL21881091 0.90 ALOX5 (0.51) ALOX5KDM4EALDH1A1GAAMAPT
SCHEMBL22854792 0.90 ALOX5 (0.58) ALOX5KDM4EALDH1A1PRKDCPIK3CD
SCHEMBL17943885 0.90 ALOX5 (0.46) ALOX5KDM4EALDH1A1GAAMAPT
SCHEMBL22854844 0.90 ALOX5 (0.57) ALOX5KDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11365167-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-06-21 US disclosed
US-20220029097-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2022-01-27 US disclosed
US-11024806-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2021-06-01 US disclosed
EP-3792235-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2021-03-17 EP disclosed
US-20210053894-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-02-25 US disclosed
EP-3481796-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-02-17 EP disclosed
US-20200259087-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-08-13 US disclosed
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2020-06-16 US disclosed
US-10566541-B2 Aromatic amine derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2020-02-18 US disclosed
US-10388885-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2019-08-20 US disclosed
US-20120056165-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-03-08 US disclosed
US-20120056165-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-03-08 US disclosed
EP-2423179-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME Idemitsu Kosan Co., Ltd. (JP) 2012-02-29 EP disclosed
EP-2423206-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME Idemitsu Kosan Co., Ltd. (JP) 2012-02-29 EP disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-02-24 US disclosed
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220029097-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALOX5 3674/4885KDM4E 586/4885ALDH1A1 470/4885
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AOC2, AOC3, H1-4 ALOX5 3902/4885KDM4E 1332/4885ALDH1A1 785/4885
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE AOC1, EBPL, CYBA ALOX5 347/4885KDM4E 1566/4885ALDH1A1 277/4885
US-20200259087-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALOX5 3674/4885KDM4E 586/4885ALDH1A1 470/4885
US-20210053894-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM ALOX5 1831/4885KDM4E 3061/4885ALDH1A1 33/4885
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same H1-4, H1-2, H1-0 ALOX5 4030/4885KDM4E 258/4885ALDH1A1 672/4885
US-11024806-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 ALOX5 3674/4885KDM4E 586/4885ALDH1A1 470/4885
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 ALOX5 3674/4885KDM4E 586/4885ALDH1A1 470/4885
US-11365167-B2 Materials for organic electroluminescent devices L1CAM, EFNA1, EPCAM ALOX5 1831/4885KDM4E 3061/4885ALDH1A1 33/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.