Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | FNTA | P49354 | 6/20 | 0.51 |
| ▸ | FNTB | P49356 | 6/20 | 0.51 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12636075 | 1.00 | CA1 (0.57) | CA1CA2FNTAFNTBGPR132 | |
| SCHEMBL989156 | 0.89 | CA2 (0.65) | CA1CA2FNTAFNTBCA12 | |
| SCHEMBL989155 | 0.89 | CA2 (0.65) | CA1CA2FNTAFNTBCA12 | |
| SCHEMBL3447634 | 0.89 | CA2 (0.65) | CA1CA2FNTAFNTBCA12 | |
| SCHEMBL28329040 | 0.89 | TAS1R3 (0.57) | CA1CA2FNTAFNTBKDM4E | |
| SCHEMBL23344426 | 0.89 | CA2 (0.59) | CA1CA2FNTAFNTBCA12 | |
| SCHEMBL22989204 | 0.89 | CA2 (0.59) | CA1CA2FNTAFNTBCA12 | |
| SCHEMBL12574343 | 0.87 | CA1 (0.47) | CA1CA2FNTAFNTBGPR132 | |
| SCHEMBL12574347 | 0.86 | CA1 (0.48) | CA1CA2FNTAFNTBGPR132 | |
| SCHEMBL12334383 | 0.85 | CA1 (0.60) | CA1CA2CA12CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575218-B2 | Thiol-containing compounds for the removal of elements from tissues and formulations therefor | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2013-11-05 | — | — | US | disclosed |
| US-8575218-B2 | Thiol-containing compounds for the removal of elements from tissues and formulations therefor | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2013-11-05 | — | — | US | disclosed |
| US-20110160150-A1 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM TISSUES AND FORMULATIONS THEREFOR | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2011-06-30 | — | — | US | disclosed |
| US-20110160150-A1 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM TISSUES AND FORMULATIONS THEREFOR | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2011-06-30 | — | — | US | disclosed |
| US-20110076246-A1 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM CONTAMINATED MILIEU AND METHODS OF USE | HALEY BOYD E | 2011-03-31 | — | — | US | disclosed |
| US-20110076246-A1 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM CONTAMINATED MILIEU AND METHODS OF USE | HALEY BOYD E | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160150-A1 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM TISSUES AND FORMULATIONS THEREFOR | SLC39A11, TST, SLC39A14 | CA1 276/4885CA2 445/4885FNTA 2618/4885 |
| US-20110076246-A1 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM CONTAMINATED MILIEU AND METHODS OF USE | TST, MPST, ARSA | CA1 7/4885CA2 37/4885FNTA 4119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.