SCHEMBL125841

SCHEMBL125841

c1cc(-c2ccc3oc4ccccc4c3c2)cc(-c2c3ccccc3c(-c3ccccc3-c3cccc4c3oc3ccccc34)c3ccccc23)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.49
PLA2G2A P14555 4/20 0.41
PLA2G4A P47712 4/20 0.41
PLA2G10 O15496 1/20 0.41
GGPS1 O95749 1/20 0.40
PRKDC P78527 5/20 0.39
NPC1 O15118 2/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
PTGES2 Q9H7Z7 1/20 0.37
PIK3CD O00329 1/20 0.36
PIK3CB P42338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22854996 0.96 ALOX5 (0.52) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL126511 0.93 ALOX5 (0.50) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL126357 0.92 ALOX5 (0.56) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL126822 0.92 ALOX5 (0.58) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL126817 0.91 ALOX5 (0.53) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL124744 0.91 ALOX5 (0.56) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL15195375 0.91 ALOX5 (0.50) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL23427251 0.90 ALOX5 (0.55) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL21450846 0.90 ALOX5 (0.55) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL20857927 0.90 ALOX5 (0.55) ALOX5PLA2G2APLA2G4APLA2G10GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220029097-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2022-01-27 US disclosed
US-11024806-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2021-06-01 US disclosed
US-20200259087-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-08-13 US disclosed
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2020-06-16 US disclosed
US-10566541-B2 Aromatic amine derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2020-02-18 US disclosed
US-10388885-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2019-08-20 US disclosed
US-20190214563-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-07-11 US disclosed
US-10270040-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2019-04-23 US disclosed
US-10263191-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2019-04-16 US disclosed
US-9991455-B2 Amine compound and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-06-05 US disclosed
US-8431250-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2013-04-30 US disclosed
US-20120181922-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120056165-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-03-08 US disclosed
US-20120056165-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-03-08 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214563-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALOX5 3674/4885PLA2G2A 4023/4885PLA2G4A 3929/4885
US-20220029097-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALOX5 3674/4885PLA2G2A 4023/4885PLA2G4A 3929/4885
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AOC2, AOC3, H1-4 ALOX5 3902/4885PLA2G2A 3455/4885PLA2G4A 3579/4885
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AR, H1-4, AFF4 ALOX5 3494/4885PLA2G2A 3921/4885PLA2G4A 3828/4885
US-20200259087-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 ALOX5 3674/4885PLA2G2A 4023/4885PLA2G4A 3929/4885
US-10263191-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 ALOX5 3674/4885PLA2G2A 4023/4885PLA2G4A 3929/4885
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same H1-4, H1-2, H1-0 ALOX5 4030/4885PLA2G2A 3874/4885PLA2G4A 4262/4885
US-10270040-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device AOC2, SQOR, AOC1 ALOX5 1204/4885PLA2G2A 4152/4885PLA2G4A 4692/4885
US-11024806-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 ALOX5 3674/4885PLA2G2A 4023/4885PLA2G4A 3929/4885
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 ALOX5 3674/4885PLA2G2A 4023/4885PLA2G4A 3929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.