Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794311 | 1.00 | TSHR (0.46) | TSHRFAAHTRPV1HIF1ALMNA | |
| SCHEMBL31619980 | 1.00 | TSHR (0.46) | TSHRFAAHTRPV1HIF1ALMNA | |
| SCHEMBL3232178 | 0.98 | TSHR (0.42) | TSHRFAAHTRPV1HIF1ALMNA | |
| SCHEMBL2455714 | 0.91 | HIF1A (0.43) | TSHRFAAHTRPV1HIF1ALMNA | |
| SCHEMBL17368843 | 0.82 | HIF1A (0.39) | TSHRFAAHTRPV1HIF1ALMNA | |
| Glutaral SCHEMBL27028184 | 0.81 | HIF1A (0.40) | TSHRTRPV1HIF1ALMNA | |
| SCHEMBL10179360 | 0.80 | MEN1 (0.35) | TSHR | |
| SCHEMBL583362 | 0.80 | ALDH1A1 (0.36) | TSHRHIF1ALMNAALDH1A1 | |
| SCHEMBL6009511 | 0.80 | LMNA (0.50) | LMNA | |
| SCHEMBL20478196 | 0.80 | LMNA (0.50) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541604-B2 | Process for the functionalization of biological molecules | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2013-09-24 | — | — | US | disclosed |
| US-20110118484-A1 | PROCESS FOR THE FUNCTIONALIZATION OF BIOLOGICAL MOLECULES | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118484-A1 | PROCESS FOR THE FUNCTIONALIZATION OF BIOLOGICAL MOLECULES | POLRMT, DNASE1, POLM | TSHR 2253/4885FAAH 2394/4885TRPV1 3406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.