SCHEMBL3232178

SCHEMBL3232178

CO[Si](CCCCC=O)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
HIF1A Q16665 1/20 0.41
FAAH O00519 2/20 0.38
TRPV1 Q8NER1 2/20 0.38
LMNA P02545 1/20 0.35
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3794311 0.98 TSHR (0.46) TSHRHIF1AFAAHTRPV1LMNA
SCHEMBL12593752 0.98 TSHR (0.46) TSHRHIF1AFAAHTRPV1LMNA
SCHEMBL31619980 0.98 TSHR (0.46) TSHRHIF1AFAAHTRPV1LMNA
SCHEMBL2455714 0.93 HIF1A (0.43) TSHRHIF1AFAAHTRPV1LMNA
SCHEMBL17368843 0.84 HIF1A (0.39) TSHRHIF1AFAAHTRPV1LMNA
Glutaral SCHEMBL27028184 0.83 HIF1A (0.40) TSHRHIF1ATRPV1LMNAMAPT
SCHEMBL583362 0.82 ALDH1A1 (0.36) TSHRHIF1ALMNAALDH1A1
SCHEMBL14270483 0.80 TSHR (0.31) TSHR
SCHEMBL3911217 0.79 TSHR (0.41) TSHRHIF1AFAAHTRPV1ALDH1A1
SCHEMBL314475 0.79 LMNA (0.46) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11840643-B2 Coating composition AXALTA COATING SYSTEMS IP CO., LLC (US) 2023-12-12 US disclosed
US-8192980-B2 Microreactor, process for the preparation thereof, and process for carrying out a biochemical or biological reaction COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2012-06-05 US disclosed
US-20100063310-A1 Functionalized silicon compounds KNEPPER JEFFREY A 2010-03-11 US disclosed
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063310-A1 Functionalized silicon compounds SIK1, MSN, SIK2 TSHR 4144/4885HIF1A 804/4885FAAH 1654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.